| The critically ill acute pancreatitis (severe acute pancreatitis,SAP) is condition bad risk, the complication are many, the case fatality rate may reach as high as 20%. Not yet completely expounded regarding the critically ill acute pancreatitis pathogenesis that, its treatment also always has the dispute, in recent years"the individuation treatment plan"in domestic and foreign gradually obtained a more unanimous approval take the non-surgery therapy as the foundation, but the critically ill acute pancreatitis conservative treatment still did not have the medicine at present. At present on clinical regarding the SAP treatment, the traditional viewpoint thought the SAP acute stage should not eat food, including in any form intestines nutrition, otherwise can make the condition to aggravate, therefore treats adopts frequently fasts, fasts generally about 3 weeks, Gives outside the entire stomach and intestines nutrition (TPN), but outside the long-term stomach and intestines the nutrition can cause the stomach and intestines mucous membrane to suffer injury, appears the gastro-intestinal tract bacterium transposition, easy to appear the infection, in particular fungus infection, moreover fasts in the patient psychology to accept with difficulty for a long time, easy to have the resistance. As soon as the growth chalone and the synonym pass through the discovery namely widely to apply in the critically ill acute pancreatitis treatment, and obtains certain effect, but the growth chalone and the synonym can cause the internal organs blood stream to reduce, will certainly to affect the stomach and intestines function the restoration; Moreover the growth chalone price is expensive, the basic unit hospital patient withstands with difficulty, simultaneously grows the chalone and the synonym to the acute pancreatitis complication formation rate and the mortality rate influence, the clinical findings are inconsistent, therefore in 2002 the 13th session of world gastrointestinal disease congress which convened in the Thai Bangkok formulates"the acute pancreatitis to diagnose the guide"not to recommend uses this kind of medicine.The motherland medicine is broad and profound, the Chinese native medicine treats the critically ill acute pancreatitis to have the glorious history and the tradition, and obtains the good effect. According to the Chinese medicine theory, the critically ill acute pancreatitis are lose sparsely, pathogenesis of the hot and damp pent up by the courage, further evolves for the painfully hot sun is flaming, stasis hot interface resistance, either on under lung, either in falls the pericardium, either the hot wound blood winds is the result of, SAP displays the abdomen full pain, or the periumbilical pain, resists according to, the bowel movement not to pass, to give off heat and so on the performance, dialectical is "Typhoid" the positive cloudy internal organs card, The compound prescription clear pancreas soup union compound prescription salvia miltiorrhiza inoculation fluid, in has the change blood rheology regarding in the critically ill acute pancreatitis treatment, improves the pancreatic gland microcycle in, passes under the merit, invigorates the blood to remove extravasted blood, alleviates fever the disintoxicating effect, simultaneously has damps the enzyme, the suppression cell factor, eliminates the oxygen free radical, protects the intestines mucous membrane, prevented the bacterium and endotoxin shifting, reduces the pancreatic gland to digestive ferment functions and so on secretion promotion pancreatic gland organization regeneration. Uses the Chinese native medicine treatment, not only the price will be inexpensive, selects material conveniently, moreover the Chinese native medicine treatment conforms to the human body physiological function, lets the gastro-intestinal tract obtain the exercise early, is advantageous eats food in the early time, and may reduce the complication and the economic burden which because long-term TPN brings, because reduces fasts for a long time the spiritual burden which brings to the patient, because also will be able soon to be normal eats food, this reduced the being hospitalized time obviously. This topic through treats the critically ill acute pancreatitis to the basic unit hospital use Chinese native medicine the treatment collection to reorganize, treats the curative effect and growth chalone synonym Austria Qu Tai through the compound prescription clear pancreas soup union compound prescription salvia miltiorrhiza inoculation fluid at the critically ill acute pancreatitis treats the critically ill acute pancreatitis (SAP) curative effect the contrast, draws up further confirms the Chinese native medicine to treat at the critically ill acute pancreatitis the function, Treats the critically ill acute pancreatitis for the Chinese native medicine to be more massively, multi-central, the stochastic double blind check experiment development provides the basis, by further the standard critically ill acute pancreatitis Chinese medicine dialectical system, expounded the Chinese medicine treats the critically ill acute pancreatitis the mechanism.Objective: Through adds the growth chalone with the foundation treatment to treat the critically ill acute pancreatitis (SAP) curative effect the contrast, the appraisal compound prescription clear pancreas soup union compound prescription salvia miltiorrhiza inoculation fluid assistance treats the critically ill acute pancreatitis (SAP)'s curative effect.Methods: To my courtyard from January ,2005 to July, 2006 to 60 example critically ill acute pancreatitis patient who admits, divides into two groups stochastically (treatment group and control group), the treatment group adds in the foundation treatment foundation with the compound prescription clear pancreas soup union compound prescription salvia miltiorrhiza inoculation fluid treatment, and with adds the control group in the foundation treatment foundation which treats with Austria Qu Tai to carry on the curative effect to compare, Observes two groups of patients symptoms body to draft vanishes thetime, the blood picture restores the normal time, the hematuriaamylase restores the normal time, the illness complication formationrate, the mortality rate, and analyzes between them whether hasstatistics significance.Results: The treatment group and the control group in Be in hospital averagely time(t=2.6,P<0.05),the anus exhaust bowel movement time(t=7.58,P<0.001), the irritability ulcer occur(X2=4.20, P<0.05), intestines paralysis occurs(X2=4.20, P<0.05), pancreatic gland or the pancreas week infection(X2=4.20, P<0.05) has the significance difference, the treatment group good in the control group, But in the symptom vanishing time(t=1.89, P>0.05), the symptom vanishing time(t=0.81, P>0.05), the white blood cell restores the normal time(t=0.41, P>0.05), hematuria amylase restores the normal time(t=0.35, P>0.05; t=0.48, P>0.05), as well as acute breath poverty-stricken syndrome ARDS(X2=0.03, P>0.05), acute kidney function failure ARF(X2=0.04, P>0.05), acute heart function failure AHF(X2=0.01, P>0.05), the acute brain function failure(X2=0.20, P>0.05), the pseudo pancreatic gland cyst(X2=0.01, P>0.05), complication in and so on death occurrences(X2=0.20, P>0.05) two groups of materials compare the non-significance difference.Conclusions: Chinese native medicine treats the critically ill acute pancreatitis to have the originality, is restoring the intestines to wriggle especially, protects the intestines mucous membrane, reduces intestinal tract bacterium infection and toxin aspects and so on absorption plays the vital role.The Chinese native medicine treats the critically ill acute pancreatitis to have selects material conveniently, the price is cheap, conforms to the human body physiology function, the curative effect is clear about, has the good research and the application prospect.The Chinese native medicine treats the critically ill acute pancreatitis to wait for many large-scale, the multi-centers, the stochastic double blind check experiment, as well as further the standard critically ill acute pancreatitis Chinese medicine dialectical system, expounded the Chinese medicine treats the critically ill acute pancreatitis the mechanism. |
PDF Full Text Request