Investigation On Abnormal Glucose Metabolism And Risk Factors Analysis In 532 Male Hypertensive Patients In The Rural Community Of Anqing, Anhui Province

Objective Abnormal glucose metabolism often occurs in essential hypertension. This condition may accelerate the development of blood vessel complication and increase the fatality rate and physical disability rate. This study investigated the incidence of abnormal glucose metabolism in rural residents with essential hypertension and explored the possible risk factors.Methods①532 male essential hypertensive patients aged 50-75 years were selected from a hypertensive clinical epidemiology study in Anhui rural community between June 2005 and February 2006. The blood pressure of enrolled subjects met the hypertension diagnosis criteria of WHO in 1999 . Patients with secondary hypertension, chronic cardiovascular disease, chronic liver, renal diseases, severe stomach intestine diseases, diabetes, hyperthyreosis, tumors and other diseases were excluded. A written informed consent was obtained from each of all participants.②All subjects were interviewed by using a health questionnaire. General medical examination was collected.③Single and multiple non-conditional Logistic regression were applied respectively to analyze the risk factors for abnormal glucose metabolism.Results All 532 subjects were enrolled in the data analysis.①There were 122 patients with abnormal fasting glucose and the total detection rate was 22.93%.Except total cholesterol and diastolic blood pressure, there were statistically significant differences in other indicators between people with normal and those with abnormal glucose metabolism (P<0.01,P<0.05).②Single Logistic regression analysis suggested that smoking, higher education, meat intake preference and other ten indicators might be the potential risk factors for abnormal glucose metabolism in this population.③Multiple factor Logistic backward-step-regression analysis showed age (≥60yr old), body mass index (≥24kg/m2), smoking, lower high density lipoprotein cholesterol(≤0.9mmol/L ), saturate cooking oil use, and favors in meat, sweet food, and salted food were significantly associated with abnormal glucose metabolism.Conclusion Detection rate of abnormal glucose metabolism is high among patients with essential hypertension in rural community. This suggests that both identification and treatment in abnormal blood glucose should be paid more attention in the treatment and primary care of hypertension. Moreover, balanced and healthy diet is important to maintain normal glucose metabolism and further to reduce the risk in cardio-celebra -vascular events in community health care.