Research About Patient's Sleep Quality, High-level Nerve Function Of High Altitude Polycythemia

[Objective]Through the questionnaire survey of high altitude polycythemia(HAPC) referring to Pittsburgh Sleep Quality Index and the Wechsler Adult Intelligence Scale,be acquaint with the patients' sleep quality,the intelligence quotient,memory condition,and the relevance between sleep quality and the high-level nerve function.[Methods]Check the blood of people who have lived on the plateau for a long time and have the multi-blood appearance,and pick out the patients of high altitude polycythemia according to the results of blood routine(RBC≥6.5×10¹²/L,Hb≥200g/L, Hct≥65%);Carry on a questionnaire survey to the patients of high altitude polycythemia by using the Pittsburgh Sleep Quality Index;For different points about PQSI(PSQI＞7 and PSQI≤7),carry on separately the questionnaire survey by using WAIS,VR,the numeric character and numeric reciting along and backwards from the end.[Results]1,In the medium altitude of Tibet plateau,the prevalence rate of HAPC, which is higher among the Han Nationality than the Tibetan national minority,and PR of those who live in a short time is higher than that of those who lived long there,is 32.60%. 2,Total PSQI score of the HAPC patients is 8.57±3.86 and sleep quality of 64 out of 100 is bad,and the others' is good.Sleep problem of HAPC patients mainly consists of the subjective sleep quality,the time of falling asleep,sleep efficiency.And the percentages of each group whose point is above two occupy respectively 38.7%,78.7%,44%,44.6% and 25.4%;the obstacles to the patients sleep quality mainly includes difficult fall-asleep and waking up easily at night or early in the morning;the percentages of people who have one or more of these problems more than 1-2 times are respectively 54.8%and 39.9%.3,The HAPC patients' intelligence quotient averages at 100.28±9.62,which is below the normal 103.60±9.22.Among them,18.7%are lower than the average,65.3% around,and 16%higher;the results of visual retention,the numeric character,numeric reciting along and backwards from the end are 7.41±1.56,12.13±2.52 and 12.81±2.07. 4,The patients who got different PSQI scores intelligence have remarkable difference in quotient and the memory condition in 10 areas(p＜0.05).5,Grade of medicine ingredients,other than hypnotic ones,of the patients is negatively related to the grade IQ and memory condition have got in their ten areas(p＜0.05).[Conclusion]1,Reports is not unanimous regarding the prevalence rate of HAPC. In this research,PR of HAPC is 32.60%in moderate altitude.Wholly speaking,it is higher in the Han Nationality than in the Tibet Minority and higher for housing time than that for long tenant.2,The problem exposed in HAPC patients' sleep quality is quite serious,and their PSQI grade is evidently higher than that of healthy people on plateau. The various kinds of components score higher mainly in sleep time.The main problem for the patients is that they have difficulty to fall asleep while are prone to wake up once fall asleep.3,Under the same anoxia environment in high altitude,cognition function withers more seriously in the patients of HAPC than normal persons without HAPC.And it mainly displays to drop in the attention span and attention mobility ability,short-time memory,complex thought judgment ability,thought flexibility and so on.4,Sleep quality of HAPC has a significant impact on their cognitive function,and poorer sleep would lead to cognitive impairment more serious.Therefore,enhancing the patients' sleep quality is an effective approach to improve their cognitive capability.