| Purpose: To study and improve the clinical diagnosis and treatment level of renal pelvis cancer.Materials and Methods:47 cases of renal pelvis cancer were analyzed retrospectively. Parameters examined include clinical manifestations , diagnosis, pathologic character operative access and prognosis.Results: 46 cases (97.9%) had hematuria as the first clinical manifestation, 27 cases had gross hematuria ;19 cases had microscopic hematuria;17 cases had lumbago accompanied with hematuria;16 cases had lumbago accompanied with hydronephrosis;5 cases accompanied with calculus;7 cases had irritative symptoms of bladder;5 cases had a fever;5 cases had lump in the pars lumbalis;3 cases had anaemia accompanied with athrepsy;5 cases had high blood pressure. All cases underwent an operation with general anesthesia. The overall 3 and 5 year survival rates of renal pelvic cancer were 65.9%(31/47) and 53.1% respectively.The 5 year survival rate was 55% in mono-focal renal pelvic cancer and 26.7%(2/7) in coexisting multi-organ carcinoma,P>0.05.The 5 year survival rate was 38.7% (12/31) in the cases with tumor>2.5 cm or 75%(12/16)in the cases with tumor≤2.5 cm,P<0.05. According to pathologic grade,the 5 year survival rate was 100%(6/6)in G1 tumor,65.2%(15/23) in G2 tumor and 16.7%(3/18)in G3 tumor,P<0.01.According pathologic stage,the 5 year survival rate was 84.6%(11/13)in T1 tumor,60%(12/20) in T2 tumor and 7.1%(1/14) in T3~T4, P<0.01. With radical nephr0uretect0my with partial bladder resection via peritoneum, the 5 year survival rate was significantly higher than that with nephrectomy or nephr0uretect0my with partial bladder resection in G2 T2 or higher tumor,P<0.05.Conclusions: Diagnosing renal pelvis cancer was mainly based on clinical manifestations, medial imaging investigation and pathological diagnosis. The pathologic grade and stage were the key point for prognosis, The radical sleeve resection of kidney, ureter and bladder was the effective method for the treatment of pelvic carcinoma. |