The Prevelence Of Retinal Vein Occlusion And Analysis Of Its Related Risk Factors In Rural Area Of North China

Purpose:To describe the prevalence of retinal central and branch vein occlusion and associated risk factors.Methods:Population-based cross-section study.From Oct 2006 to Oct 2007,to identify retinal vein occlusion in baseline,6830 participants in Handan City,Hebei Province were undertook physical and ocular examination including taking fundus digital images,trained ophthamology specialists graded all fundus images.Prevelence and standardized prevelence of central retinal vein occlusion and branch retinal vein occlusion were calculated according to the population-age distribution indices baseed on the 5th population census of China in 2000,selected cases with branch retinal vein occlusion are the study group and the others of 6636 participants having been took the fundus digital images are controled group.Binary logistical regression was used to analyze the risk factors related to branch retinal vein occlusion and obtain the OR(odd ratio)values.Results:55 cases with retinal vein occlusion including 50 cases of branch vein occlusion and 5 cases of central retinal vein occlusion.The prevelence of branch retinal vein occlusion and central retinal vein occlusion is 0.7%and 0.1%,respectively;the stardardized prevelence of branch retinal vein occlusion and central retinal vein occlusion is 0.53% and 0.04%,respectively,according to the the population-age distribution indices based on the 5th population census of China;While adjusting for age,branch retinal vein occlusion is associated to hypertension history(OR=2.9,P＜0.001),systolic blood pressure(SBP)(OR=1.8 for 10 mm Hg,P＜0.001),diastolic blood pressure(DBP)(OR=1.6 for 10 mm Hg,P＜0.001),pulse pressure(PP)(OR=1.0 for 10 mm Hg, P=0.007),perfusion pressure(OR=1.5 for 10 mm Hg,P=0.010),passive smoking history(OR=1.0,P=0.038).Conclusion:Retinal vein occlusion is infrequent in the population which pathology is still partially covered at present.1.Without severe complications the visual acuity of cases with BRVO is relatively good; 2.The prevelence of branch retinal vein occlusion and central retinal vein occlusion is 0.7%and 0.1%2;3.These data suggest a strong association between branch retinal vein occlusion and blood pressure,which may signals the potential association beweent branch retinal vein occlusion and cardiovascular and cerebrovascular diseases;4.Data from larger populations are needed to further assess associations between risk factors and retinal vein occlusions.