The Geographical Distribution Of Normal Reference Value Of Four Parameters Of Blood Gas Analysis

中青年Y_TCO2=30.76-0.002448X₁-0.07166X₆±2.29中老年Y_TCO2=27.15-0.002245X₁-0.002935X₇±1.19(?)_BB=50.68-0.8544lnX₁±3.54选取有代表性的地点进行估算和验证,然后将所估算的预测值与当地的实测值进行比较,通过单因素方差法对预测值和实测值进行检验,发现利用模型估算出的预测值和实测值一致性很好,无显著性差异(P>0.05)。研究取得的结论与创新之处:如果知道了中国某地的地理因素,就可以用回归方程计算这个地区的动脉血实际碳酸氢根(AB),标准碳酸氢根(SB),二氧化碳总量(TCO₂)和缓冲碱(BB)正常参考值。依据血气分析正常参考值与地理因素的依赖关系,把中国分为八个区。通过对所收集的各地区动脉血气分析四项指标的正常参考值与地理因素指标之间进行的回归分析并选择最优回归模型进行预测,说明这些回归模型可以有效的预测某一地区的动脉血实际碳酸氢根(AB),标准碳酸氢根(SB),二氧化碳总量(TCO₂)和缓冲碱(BB)正常参考值,应用此模型可以从各地的地理因素着手,方便的估算和验证中国任何地区的成年人动脉血实际碳酸氢根(AB),标准碳酸氢根(SB),二氧化碳总量(TCO₂)和缓冲碱(BB)正常参考值。本论文的创新之处在于对中国健康成年人动脉血实际碳酸氢根(AB),标准碳酸氢根(SB),二氧化碳总量(TCO₂)和缓冲碱(BB)正常参考值和地理因素进行定量化研究,虽然也有沙志英,刘传兰,田广智等少数医学工作者的研究涉及到某地区血气分析某项指标或多项指标的正常参考值,但也仅仅是定性描述,像本文这样对成年人动脉血实际碳酸氢根(AB),标准碳酸氢根(SB),二氧化碳总量(TCO₂)和缓冲碱(BB)正常参考值与地理因素进行定量研究,从整个地理环境着手,整体研究中国这一大的区域,国内外还未见报道。 carbon dioxide (TCO₂) and alkaline buffer (BB) in domestic and external which affects the accuracy ofdiagnose seriously. This paper aims at supplying a scientific basis for unifying the normal referencevalue standard of actual bicarbonate (AB), standard bicarbonate (SB), total carbon dioxide (TCO₂) andalkaline buffer (BB) of Chinese adults. This research is helpful to enrich the content of clinicalmedicine and the laboratory medicine, enables the clinical medical worker to be possible forecasts thenormal reference value of adults' artery blood actual bicarbonate (AB), standard bicarbonate (SB), totalcarbon dioxide (TCO₂) and alkaline buffer (BB) in this area according to the locality in the clinicalworking, thus it is helpful to judges adult's state of health and adopts different protection and curingmethod promptly.The theory basis, methods and process: This paper depend on the blood gas analysis theory, themedical geography theory, the physiographic theory and the mathematical statistic principle as thebasis, using the SPSS statistics software, Excel computer methods, ArcGis, CorelDRAW and so on,studies the relationship of the normal reference value of adults' artery blood actual bicarbonate (AB),standard bicarbonate (SB), total carbon dioxide (TCO₂) and alkaline buffer (BB) and the geographicalfactors. Collected lots of the data from various region by searching and buying literatures, then wechoose four from the parameters of blood gas analysis, such as actual bicarbonate (AB), standardbicarbonate (SB), total carbon dioxide (TCO₂) and alkaline buffer (BB) in this thesis. According to therelational geographical literature and interrelated literature, we choose eight parameters of geographicalfactors: altitude, the annual sunshine duration, annual percentage of sunshine duration, the annualaverage temperature, the annual range of air temperature, the annual mean relative humidity, annualrainfall, annual mean wind speed. Then do linear analysis, stepwise regression analysis, multiple linearregression analysis and non linear regression analysis between each of the medical parameters and theeight geographical factors, then we got a series of regression equation. On the basis of the optimizedtheory, we choose the best one from the gotten regression equation. On the base of the best regressionmodel, we choose the most representative point to^carries on comparison and make feasibility testbetween the test data and numeric forecast from the model, using the method of the single factor test.Finally discover the actual value and model forecast value uniform very good, so we can use the modelto forecast the normal reference value of the adults' artery blood in each place. Using the methods oflinear analysis, stepwise regression analysis, multiple linear regression analysis and non-linearregression analysis and get the best regression model of adults' artery blood actual bicarbonate (AB),standard bicarbonate (SB), total carbon dioxide (TCO₂) and alkaline buffer (BB) and geographicalfactors are :18-40 years old: YAB =24.19-0.001593X₁±2.15 41-80 years old: (?)=24.89-(?)±2.53Adults: YSB=24.81-0.0006845X₁-0.4171X₈±1.25025xl.9618-40 years old: Y_TCO₂=30.76-0.002448X1-0.07166X₆±2.29465xl.9641-80years old: Y_TCO₂=27.15-0.002245X₁-0.002935X₇±1.19206xl.96Adults: (?)Y_BB=50.68-0.85441nX₁±3.54Then choose the best representative point to make estimates and confirms, and compare them, using themethod of the single factor test, we find the data from model and the test data upstair accordant, havingno remarkable difference (P>0.05)。The results and innovation: If geographical values are obtained in some areas, the normalreference value of actual bicarbonate (AB), standard bicarbonate (SB), total carbon dioxide (TCO₂) andalkaline buffer (BB) of this area can be reckoned using the regression equations. Furthermore,according to the similarity of the normal reference value of artery blood analysis, China can be dividedinto eight regions. By the method of regression analysis between four normal reference values ofarterial blood gas analysis collected in various regions and geographical factors, predict one of the bestregression models. This regression model can be effectively predict arterial blood gas analysisincluding actual bicarbonate (AB), standard bicarbonate (SB), total carbon dioxide (TCO₂) and alkalinebuffer (BB). The geographical factors in this model can be easily gained, it is facilitate to estimate andverify any region of normal reference values of the adults' arterial blood gas analysis actual bicarbonate(AB), standard bicarbonate (SB), total carbon dioxide (TCO₂) and alkaline buffer (BB) in China.This paper's innovation lies to the quantitative research of the normal reference value of Chinesehealthy adults' artery blood actual bicarbonate (AB), standard bicarbonate (SB), total carbon dioxide(TCO₂) and alkaline buffer (BB) and the geographical factors, although it has minority medicineworker's research to involved the normal reference value of blood gas analyzes one parameter or someparameters in some local such as Sha Zhiying, Liu Chuanlan, Tian Guangzhi and so on, but it is merelythe qualitative description. So just like this article's quantitative investigation between the normalreference value of adults' artery blood actual bicarbonate (AB), standard bicarbonate (SB), total carbondioxide (TCO₂) and alkaline buffer (BB) and the geographical factors, and researches the wholeChinese geographical environment, has not seen the report at home and abroad.