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Analysis Of Multi-factor Of Esophageal Cancer Postoperative Respiratory Failure

Posted on:2010-07-18Degree:MasterType:Thesis
Country:ChinaCandidate:S LiuFull Text:PDF
GTID:2144360275456927Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective:To investigate the main risk factors of postoperative occurred respiratory failure of esophageal cancer,as a basis for guiding clinical that prevent its occurrence Targeted.Methods:170 cases of esophageal cancer postoperative patients were divided into 31 cases of postoperative occur respiratory failure and 139 cases postoperative patients with did not occur respiratory failure,the independent samples t tests,the completely randomized design fourfold table information x2 test and the completely randomized design two-sample rank sum test that them preliminary single factor analysis relevanceon of information of two groups patients and postoperative respiratory failure,information of two groups patients have age,sex,smoking index,nutritional status,preoperative lung function,Whether preoperative respiratory diseases,preoperative blood test,anastomotic location,operative time,Tumor site etc,selected statistically significant variables from the results of the analysis,then,Further multi-factor Logistic regression analysis,the relative risk(RR) of Variables was calculated, OR=EXP(β),get the conclusion that Logistic regression prediction model finally,evaluated the accuracy of the model,the above adopt Spssl3.0 software statistical calculation and analysis。Results:Initial use of t tests,x2 test,rank sum test single-factor analysis for clinical indicators and get that which wcrc plasma albumin concent,age,Blood total cholesterol,The merger history of preoperative cardiovascular,preoperative combined respiratory diseases,cigaret index,body weight index,the volume of total liquid of Day surgery,Loss of blood volume of During surgery and preoperative,operating time,neck Anastomosis,Chest complications after operation,preoperative pulmonary function(MVV<50%,FEV1<1.5L,FVC<80%),nutritional status,Tumor length,Tumor site,Tumor clinical staging were statistically significant(P<0.05)。Clinical indicators of the above entry Backward and logistic regression analysis of factors combined with clinical,Calculated 7 factors,These factors Divided into Chest complications after operation X1(OR=4.017),ageX2(OR=2.481)MVV<50%X3(OR=2.311),preoperative combined respiratory diseases X4(OR=2.157),smoking index X5(OR=2.037),operating time X6(OR=1.067),nutritional status X7(OR=0.875) by Descending to affect postoperative respiratory failure。calculated the Logistic regression prediction model following:1n(p/(1-p))=-4.213±1.063X1+0.938X2+0.834X3+0.731X4+0.649X5+0.538X6+0.347 X7。Conclusion:Chest complications after operation,age,MVV<50%,preoperative combined respiratory diseases,smoking index,operating time,nutritional status were main risk factors of postoperative occurred respiratory failure of esophageal cancer,then establish corresponding Logistic Regression Model。...
Keywords/Search Tags:Respiratory Failure, risk factors, Prediction model, esophageal cancer, Surgical treatment
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