Research Advance Of Brain Injury Mechamism And Brain Protective Measures In Cardiopulmonary Bypass

With the rapid development of cardiovascular technology, postoperative complications and mortality of heart diseases decreased significantly, but the incidence of postoperative brain dysfunction is still very high. At present, the main pathogenesis machanism are closed with the decreasement of cerebral blood flow during the operaion, appearence of brain micro-suppository, excitatory neurotransmitter releasing and the systemic inflammatory response and so on. Scholors has put more attention on brain protection problems. In recent years, demostic and abroad scholars mainly focus on the cardiopulmonary bypass techniques, steady-state management of blood gas and use of brain protetive medicines. Until now significant progress has been made.