| Objective: To investigate the impact of vacuum-assisted closure and biological dressing in wound repair.Methods 77 cases of patients with soft tissue injury of the department of Burns plastic surgery of Fourth Affiliated Hospital of Guangxi Medical University from September 2007 to February 2009 are grouped by admission date in accordance with randomized, 40 cases of single-day admission are put into the study group ,and 37 cases of double-day admission are put into the control group.Patients of the study group accept the therapy of VAC and second stage epidermal skin graft. Patients of the control group accept the therapy of biological dressing and second stage epidermal skin graft.10 cases and 8 cases respectively of the study group and control group do not complete the therapy plan. So there are respectively 30 and 29 patients complete the plan,and enter the final analysis.Results Among the 30 patients of study group ,8 cases recover, 13 cases are markedly effective, 6 cases are improved, 3 cases are ineffective, the total effective rate is 90%, the average wound healing time is 17.1 days;Among 29 cases of patients of the control group, 3 cases recover, 10 cases are markedly effective, 8 cases are improved, 8 cases are ineffective, the total effective rate is 72%, the average wound healing time is 24.2 days.The statistically differences of two groups are significant in efficacy. (P <0.05).Conclusion vacuum-assisted closure provides a new way of thinking and means for clinical wound healing ,and it should be spreaded to be used.
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