The Clinical Observation Of Radiofrequency Ablation In The Treatment Of Pulmonary Malignant Tumor

ObjectiveRadiofrequency ablation(RFA) is a minimally invasive local technique used to treat non-small cell lung cancer(NSCLC).This study observes the clinical efficacy and safety of RFA using cooled-tip electrode in the treatment of pulmonary malignant tumor.Methods19 lesions of 14 patients with pulmonary malignant tumor,including non-small cell lung cancer(nsclc) in 10 cases and metastatic lung tumor in 4 cases,were treated by percutaneous radiofrequency ablation.All patients were not surgical candidates either due to advanced stage or due to comorbid conditions.All patients were diagnosed as m tumor clinically and pathologically.The procedure was performed under local anesthesia and conscious sedation.All lesions were evaluated by CT scan after radiofrequency ablation.quality of life(QOL ) was assessed by karnofsky performance scale(KPS).ResultsThere were 12 men and 2 women ranging from 52 to 75 years old.There are 12 lesions less than 3cm in diameter,and 7 lesions ranging from 3cm to 5cm in diameter.9 lesions were treated with overlapping ablations more than 2 times,3 patients were lost to follow-up.80%lesions achieved complete ablation in lesions less than 3cm 1 month later,but 50%of complete ablation in lesions ranging from 3cm to 5cm in diameter.The total complete ablation rate was 68.75%in 16 lesions.The median quality of life score was significantly higher in post-RFA patients than those before RFA.Postoperative complications is well tolerated.ConclusionsRadiofrequency ablation is effective and safe in treating primary advanced non-small cell lung cancer and metastatic of tumors in lung.Also can improve the quality of life by RFA.We suggested that RFA shall be further investigated for clinical application.