Reliability And Validity Of A Chinese Version Of The Quality Of Life In Epilepsy Inventory (QOLIE-31-P)

Objective:The aim of the work described here was to develop and validate a Chinese version of the Patient-Weighted Quality of Life in Epilepsy Questionnaire (QOLIE-31-P),and use this scale to survey and analyze some influential factors for quality of life in adults with epilepsy.Participants:A total of 200 adults with epilepsy,selected from the epilepsy center of the second affiliated hospital Zhejiang University College of medicine.Subjects were more than 18 years old and had to have at least 9 years of education,be able to read and comprehend the questions,to have had epilepsy for at least 1 year,and had to have experienced seizures during the last 6 months.Methods:The original English version of the QOLIE-31-P was translated into the Chinese language.The inventory was then completed by 200 adult patients with epilepsy.49 patients also completed the scale twice within three weeks.Test-retest, internal consistency reliabilities,construct validity,and some influential factors for quality of life in adults with epilepsy were assessed.Results:Test-retest reliability(Pearson's correlation coefficient) for the Chinese version of the QOLIE-31-P ranged from 0.725 to 0.912(P＜0.001),and the internal consistency reliability(Cronbach's a coefficient) ranged from 0.627 to 0.898.Factor analysis showed that there are seven factors,and explain the total variance for about 64.9%,and the domain scores ranged from 41.0 to 63.9.The final score of the quality of 200 patients was 59.3±17.8,and it showed that the most three concerned items were seizure worry,medication effects,and overall quality of life seizure.Frequency affected the quality of life of adults with epilepsy,the coefficient was -3.43(P＜0.05),the QOLIE-31-P score of the patients with tonic clonic seizure was 55.7±16.6,and that of other seizure type was 61.4±18.7(t=-2.568,P＜0.05).Conclusions:The psychometric properties of the Chinese version of the QOLIE-31-P are good and similar to those of the American version,have good reliability and validity,and can be applied to assess quality of life in adult patients with epilepsy in China.Seizure frequence has negative correlation with the quality of life. The quality of life of the patients with tonic clonic seizure is poorer than those with other seizure types,with significant deviation.