Quantitative Analysis Of Psychiatric Disorders In Vertiginous Patients

Objective To investigate the relationship between psychological disorder and vestibular dysfunction in patients suffering from vertigo,and to measure patients' quality of life after intratympanic gentamicin surgery.Method Retrospective study of 17 patients with peripheral vestibular dysfunction recruited from the EENT hospital whom underwent intratympanic gentamicin injection.Hospital Anxiety and Depression scale,Self-rating Anxiety scale, Self-rating Depression scale,Symptom Checklist-90 were used.Pre- and postoperative scores where compared.The QOL of the 17 vertiginous patients were assessed with the Meniere's Disease Outcome Questionnaire.Results The outcomes of Hospital Anxiety and Depression scale,Self-rating Anxiety scale,Self-rating Depression scale,Symptom Checklist-90 are significantly greater in vertiginous group than that in normal controls(P＜0.001).The preoperative scores of these 4 questionnaires are greater than the postoperative scores in vertiginous patients (P＜0.05).No significant difference was noted between male and female participants in all the questionnaires used(P＞0.05).Overall,the mean change in QOL score was 40.1points(P＜0.001),the change in Meniere's Disease Outcome Questionnaire quality-of-life score was highly correlated with that of the global question score(P＜0.05).Conclusion Significant differences were noted between vertiginous patients and normal controls in psychiatric questionnaires,suggesting that psychological dysfunction may contribute to the vertigo episode.Vertiginous patients' quality of life have significant improvement after intratympanic gentamicin surgery.