Behavioral And ERP Study On Heroin Abstainers' Attentional Bias

Drug dependence includes physical dependence and psychological dependence. Relapse is key to cure drug abusers , and psychological dependence is the main reason of relapse. Attentional bias is the main area on cognition study of drug dependence. Attentional bias on drug-related cue has been suggested for two decades. Most learners contend that is a fact. They demonstrate the theory by means of testing reaction time and recording EEG. In China, heroin prevail more extensively than other drugs. At present, there are several literatures about attentional bias on heroin-related cues overseas. No one deploy the emotional Stroop to study the attentional bias in China yet.The present research tried to approach the cognitive mode of heroin abusers . To erect two reference , including neutral and evocative picture, We draw some conclusions. We chose neutral and evocative picture of no emotional motivation from IAPS so as to acquire motivational trait to emotion of heroin-related picture.Some main conclusions were drawn as follows:The main effect was found for cue overall. The RT of heroin-related picture was longer than neutral picture in patients. There was no difference between RT of evocative picture and heroin-related picture in patients. The RT of heroin-related picture in patients was longer than healthy control subjects. These result provide evidence for attentional bias.The reaction mode of patients was different from healthy control subjects. Ragard to amplitude of P300 and SSPW, we draw a conclusion that the amplitude for heroin-related picture was equal to evocative picture and was more than neutral picture in patients, but in healthy control subjects the amplitude for heroin-related picture was equal to neutral picture and less than evocative picture.Someone contend that left frontal sites would be more responsive when subjects were experiencing heroin-related pictures as appetitive. The present research found that amplitude of SSPW was higher at F3 site than right site. We support the standpoint.A significant interaction between cue and group was found for SSPW. This indicate that amplitude induced by heroin-related pictures was higher than neutral pictures and that amplitude of patients was higher than healthy control subjects.Although a significant main effect was found for P300, it would be approached whether it may be regarded as sensitive index.The present research made a meaningful attempt to compare the three cue stimuli. It's conceivable that human beings will get more systematic understanding about their neurobiological bases and functions with the development of cognitve neuroscience, brain neuroimaging and electrophysiological technology.