The Clinical Study Of Transient Intraocular Pressure Elevation After Vitreoretinal Surgery

Objective: Transient elevation of intraocular pressure (IOP) is a frequent occurrence after vitreoretinal surgery. Severe pressure elevation may result in visual loss. To investigate the incidence and related risk factors of IOP elevation in patients who have undergone vitreoretinal surgery. To determine the characteristic and regularity of variability of intraocular pressure (IOP) during earlier period from the baseline after vitreoretinal surgery.Methods: We retrospectively study a total of 121 eyes in 121 patients who underwent vitreoretinal surgery in our department and analysis the factors that may be related to the state of high ocular pressure. The relationship of occurrence of the time of onset and duration of persistence of postoperative ocular hypertension with the age, the different kinds of primary diseases, the techniques of operation used, and the condition whether or not the affected eyes had formerly accepted surgical intervention, were analyzed.Results: The IOP occurred in 45 eyes after operation (37.19%). The rates of IOP elevation of the male and female were 36.62% and 38.00% respectively, without statistical significance (P﹥0.05). But there is outstanding increase in elevation rate of IOP with age (P<0.05). The probability of postoperative IOP elevation in the patients suffered from the retinal detachment with proliferative vitreoretinopathy (PVR)≥grade C2 was the highest in all the patients in our study (48.39%, P<0.05). The patients who had intraocular surgery before were more likely to have IOP elevation than the ones without intraocular surgery (P<0.05). The rate of IOP elevation with lens extraction or not was 29.27% and 41.25%, the difference being not remarkable (P﹥0.05). The rate of IOP elevation with scatter endophotocoagulation or partial endophotocoagulation was 46.55% and 28.57%, there were statistically significant difference between them (P<0.05). The rate of IOP elevation with intraocular tamponade of silicone oil, C2F6, SF6 or none was 47.62%, 60.00%, 46.67% and 12.82% respectively, the difference being outstanding (P<0.05). Intraocular surgery and intraocular tamponade were the risk factors by Logistic regression analyze.Conclusions: A variety of reasons have been caused by one or sustained increase in intraocular pressure occurred in a higher proportion of vitreoretinal surgery. IOP elevation was a common clinical complication of vitreoretinal surgery. The previous intraocular surgeries, certain primary eye disease and combined ocular procedures are the risk factors of IOP elevation after PPV.