The Analysis Of Risk Factors Of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography And Prevention Strategy

Objective: To analyze the possible risk factors for post-endoscopic retrograde cholangiopancreatography pancreatitis(PEP).Methods: The clinical materials of 956 patients who underwent endoscopic retrograde cholangiopancreatography(ERCP) in Chongqing the Third Hospital from July 1997 to October 2007 were analyzed retrospectively. The investigated factors including intraoperative intravenous analgesia, pancreatic duct opacification, bile duct cannulation failure, endoscopic sphincterotomy(EST),duration of ERCP procedure,bile duct dilatation,jaundice,the history of pancreatitis, hypertension, diabetes, gender and age.Results: The incidence of PEP significantly increased in patients with pancreatic duct opacification ,bile duct cannulation failure,EST,long duration of ERCP,non-jaundice, history of pancreatitis, young or middle age(P<0.01).While intraoperative intravenous analgesia, bile duct dilatation, hypertension,diabetes and gender didn't influence the incidence of PEP (P>0.05).Conclusion: Pancreatic duct opacification,bile duct cannulation failure,EST,long duration of ERCP,non-jaundice, history of pancreatitis and young or middle age are all risk factors for PEP. While intraoperative intravenous analgesia, bile duct dilatation, hypertension,diabetes and gender are not risk factors for PEP. Proper prevention strategy can decrease the incidence of PEP.