Analysis Of Therapeutic Effect Of Treating Osteoporosis Vertebral Compression Fractures With Percutaneous Vertebroplasty

BACKGROUND: Osteoporosis is a widespread public health problem in China. Vertebral body compression fractures are among the most common complications of osteoporosis. The lifetime risk of osteoporotic spine fracture in women is 15. 6%. Each year, a lot of vertebral body fractures secondary to osteoporosis are diagnosed in China. The major consequences of osteoporotic compression fractures are back pain, kyphosis, and height loss. As vertebroplasty utilization was becoming wide spread, kyphoplasty was introduced as an alternative approach. Kyphoplasty entails inflation of a percutaneously delivered balloon in the vertebral body, followed by the percutaneous injection of bone cement into the cavity created by the balloon. The balloon is intended to restore the vertebral body height while creating a cavity to be filled with bone cement. Percutaneous vertebroplasty and kyphoplasty both are now widely used to treat osteoporotic compression fractures.OBJECTIVE: To evaluate and compare clinical results of PVP and PKP performed on patients of osteoporotic vertebral compression fracture.METHODS: we reviewed 45 cases of osteoporosis vertebral compression fractures from February, 2005 to April,2007. There were 12 males and 33 females with an average age of 64 years.In all of the cases,4 cases were at T11, 9 cases were at T12, 27 cases were at L1, 19 cases were at L2, 8 cases were at L3 and 3 caseswere at L4. 25 of 45 patients were treated with PVP and 20 patientsunderwent PKP. The results of vertebral body and disc height, Cobb angle,VAS and ODI were separately compared between the PVP group and the PKPgroup.RESULTS: All patients had successful intervention and marked orcomplete pain relief. There was a significant difference of vertebralbody and disc height, Cobb angle and ODI between the two groupspostoperatively ( P < 0. 05).CONCLUSIONS: Compared to the patients of PVP group, the patientstreated with PKP showed more satisfactory results of improvement ofvertebral body and disc height, the spinal function, spinal kyphosis anddisplayed lower incidence of cement leakage.