Comparison Of Several Current Continuous Glucose Monitoring System And Their Clinical Applications

Continuous Glucose Monitoring System(CGMS)is a new glucose monitoring apparatus with huge advantages in discovery of asymptomatic hypoglycemia, revealing glycemic excursion, etc. This review summarizes the differences among several common CGMS in the world,the clinical applications and the future of the new generation of CGMS and its development trends. Nine kinds of CGMS have got FDA and/or CE approval to be available in the United States and/or Europe, most of which are minimally invasive using subcutaneous glucose sensor to monitor interstitial fluid glucose, while only two types of glucose sensor are on the surface of the skin. Interstitial fluid glucose measured by CGMS are significantly correlated with venous blood glucose and capillary blood glucose, so CGMS can be used as an auxiliary means to monitor glucose. CGMS has become more and more common, and it can be used in type 1 diabetes, type 2 diabetes, gestational diabetes, specific types of diabetes, diabetic emergencies, islet cell transplantation etc. to improve blood glucose control, reduce diabetes-related incidents, and improve the quality of life. CGMS has shown its unique advantages in clinical application, so we can predict that the built-in closed-loop system in development will become the main treatment for diabetes in the near future.