The Clinical Evaluation Of The Method Of Tonifying Kidney, Clearing Damp-heat And Activating Blood Treating MsPGN

Tonifying kidney, clearing damp-heat and activating blood is an effective method to treat chronic glomerulonephritis, which has been summarized by my instructor from his long clinical practice. According to this clinical study, 55 cases of biopsy for definite diagnosis of primary mesangial proliferative glomerulonephritis in patients was divided into four groups of treatmentgroup, analysising of urinary protein, urine red blood cell count, such as target-related effects, further affirmed the method of tonifying kidney, clearing damp-heat and activating blood has a good clinical efficacy.Objective:Assess the clinical efficacy of the method of tonifying kidney, clearing damp-heat and activating blood for treatment of primary mesangial proliferative glomerulonephritis.Method:Selection from August 2007 to February 2009 Nanjing University of Traditional Chinese Medicine, Affiliated Hospital of Nephrology-patient and outpatient services for patients with more complete information on 55 cases, are in line with the primary mesangial proliferative glomerulonephritis of the Western diagnosis, according to urinary protein stratified for quantitative urine protein <1.0g/24h (A group) and 1.0g/24h = urinary protein <3.5g/24h (B group), then A, B groups were randomly divided into test group and control group. A, B groups were given jiahuapian and Tripterygium wilfordii tablets Separately. Treatment group Add with tonifying kidney, clearing damp-heat and activating blood medicine. Course of 2 months after the end of treatment were observed A, B were the control group before and after the treatment group were urinary protein characterization, a 24-hour urinary protein, urinary occult blood, urine red blood cells and the target quantity, such as traditional Chinese medicine symptoms, signs and syndromes points changes in rating law tonifying kidney, clearing damp-heat and activating blood of primary mesangial proliferative glomerulonephritis clinical efficacy.Results:After the treatment, the results show that the method of tonifying kidney, clearing damp-heat and activating blood can significantly reduce the primary mesangial proliferative glomerulonephritis in patients with urine protein and urine red blood cell count, be able to consolidate the efficacy of continuous improvement target, has good clinical efficacy, but also a marked improvement in patients with symptoms, improve quality of life.Conclusion:Kidney insufficiency,damp (heat) and blood stasis were the main mechanisms of MsPGN. Kidney insufficiency was the base of occurrence. Damp (heat) and blood stasis was the key mechanisms of progression. So tonifying kidney, cleariny damp-heat and activating blood were the main methods of treatment on MsPGN.