Seabuckthorn Oil On Sulfur Dioxide Pollution Of The Environment Movement Of Rat Cardiac And Skeletal Muscle Lipid Peroxidation Level Of Intervention Research

The various effects of sea buckthorn oil have a connection with itsnutrient compositions, which contain a variety of amino acids, enzymes, mineralelements, vitamins, flavonoids and other substances. Sea buckthorn oil and itsproducts already have started a great success in the fields of daily use,pharmaceutical, beauty, healthy and food research. Sulfur dioxide (SO2) is acommon large harmful atmospheric pollutant to human health, when it is absorbedinto the human body, first in the body it fluids into its metabolic derivatives- sodium sulfite (Na2SO3) and sodium bisulfite (NaHSO3),which can causebronchitis, asthma, emphysema and other respiratory diseases, and even relatedto the occurrence of lung cancer.SO2 inhalation is generally believed thatmammals can cause lipid peroxidation, resulting in a large number of freeradicals, which attack the cell membrane system, resulting in disordered cellstructure. Studies have shown that sea buckthorn oil, antioxidant and otherpharmacological effects and its anti-free radical oxidation can obviouslyimprove the SO2 on myocardial cell injury, myocardial tissue and the ability ofanti-free radical oxidation. In this paper, on the whole animal level, usinglow-pressure oxygen warehouse simulation of different concentrations of SO2pollution in the environment, it sets up animal training model, usephysiological and biochemical theories and methods, and statistical analysisthe different concentrations of SO2 inhalation rat cardiac and skeletal muscleglutathione oxidation restore the dynamic changes in the laws. At last thepaper reveals the supplementary test passers sea buckthorn oil oral liquid onthe nutritional status of rats with exercise, exercise capacity, free radicaldefense system, the impact of myocardial skeletal muscle, for the developmentof sea buckthorn plants to reduce SO2 air harmful and as a health food sportsproviding a reference.Experimental Methods: Use two healthy male 48-month-old wistar rats, bodyweight at 130±20g, by the experimental feeding, all rats in the adaptabilityof the experiment one week after feeding. Required the control group wererandomly divided into quiet, simple exercise group, SO2 Sports Group II +, SO2+ II sports + Hippophae oil group, SO2Ⅲ+ exercise group, SO2Ⅲ+ sports +sea buckthorn oil. Components of the cage Promulgated in accordance withnational standards for air pollution concentrations, to create a man-madeenvironment SO2 exposure. Experimental group at 1 cubic meter of SO2 pollutionin fumigation box type exposure, exposure + sports daily oral medication Seabuckthorn oil, administration of 2.5ml per kg body weight administration, theother four groups were irrigated serving the same volume of normal saline. Rats in the nor moxic or SO2 pollution in the environment Treadmill Training, everyday, both at 8:00-12:00, speed increased from 15m/min to 30m/min, time 20m/min,the gradient is zero. Relapse after the end of four weeks training in the fifthweek on Monday after the decapitation death, the rats were measured by cardiacand skeletal muscle superoxide dismutase (SOD), Catalasing(CAT) andglutathione-off peroxidase(GSH-Px) activity and malondialdehyde (MDA) content.The experimental results:1. After 4 weeks of exposure medication training, body weight of rats ineach group were all natural growth.2. And quiet group, sports group rat cardiac and skeletal muscle tissuemalondialdehyde (MDA) content must show the upward trend, superoxide dismutase(SOD), catalase (CAT), Valley glutathione peroxidase (GSH-PX) activity inrelative decline. 2 + exercise group SO2myocardium, skeletal muscle tissue MDA content increased significantly (P<0.05), SOD, CAT, GSH-PX activity was significantly reduced (P <0.05). SO2 +exercise group three cardiac and skeletal muscle tissue MDA content wassignificantly increased (P <0.01), SOD, CAT, GSH-PX activity significantlydecreased (P <0.01).Compared with the exercise group, SO2 II + Sports Group myocardium,skeletal muscle tissue MDA content increased significantly (P <0.05), SOD, CAT,GSH-PX activity was significantly reduced (P <0.05). SO2 + exercise groupⅢcardiac and skeletal muscle tissue MDA content was significantly increased (P<0.01), SOD, CAT, GSH-PX activity significantly decreased (P <0.01).3. Sea buckthorn oil oral supplement to enhance myocardial exercise, antifreeradical oxidation in skeletal muscle function, as follows: At the sameconcentration of SO2 pollution exercise, oral MDA content of sea buckthorn oilgroup was significantly lower than exposure group exercise, SOD, CAT, GSH-PXactivity than the group exposed to exercise. Different concentrations ofpollution, SO2Ⅱ+ sport + sea buckthorn oil group (D group) was significantlylower than theⅢ-tier + sports + SO2 sea buckthorn oil group (F group), (P<0.05).4. Different organizations in the same state, MDA content, SOD, CAT, GSH-PXactivity is not the same; at the same organization under different conditions,MDA content, SOD, CAT, GSH-PX activity is not the same, which may react tissuesand organs of the General antioxidant capabilities.Through the experimental findings of a study of SO2 pollution exerciseenvironment Sea buckthorn oil taking oral rat enhance the body's ability tofree radical defense system, to improve the pollution of the environment and the exercise of the adverse effect of the body, the body of the delay there isa certain degree of fatigue role in enhancing the capacity of the exercise inrats.