| BACKGROUND: Peripheral nerve injury is a common trauma hand surgery diseases. Peripheral nerve may be due to compression, stretching, cutting, etc., causing injury, clinical manifestations of sensory impairment or movement disorders. Slower growth rate due to nerve and skeletal muscle due to loss of nutritional support after nerves easy to rapidly declining, and even loss of limb function. Thus, after peripheral nerve injury repair speed of a direct impact on patient quality of life. Studies have shown that: the structure of peripheral nerve injury and nerve regeneration and functional recovery of micro-environment. Sound waves, light waves, magnetic fields, electrical stimulation, etc. by changing various physical therapy can be micro-environment on nerve regeneration after peripheral nerve injury repair are facilitated. But on the choice of different physical therapy needs further study.Objective: To observe the physical treatment of the rabbits go into repair damaged peripheral role in promoting, and compare, to get the best treatment.Methods: (1) Select the 64 healthy adult rabbits of either gender, were randomly divided into ultrasonic treatment group, frequency electrical stimulation, infrared treatment group and control group 16. Sharp break from the tibial nerve without injury after the 9-0 epineurial suture by suture nerve repair. After 3 day, in addition to the control group, the three experimental groups were using the CD-1A-CII ultrasound therapeutic apparatus, HY-D02-type frequency therapeutic equipment and computer YP infrared therapeutic apparatus for treatment, 20min / day, time, observation point as 4 weeks and 8 weeks. (2), respectively, after treatment for 4 weeks and 8 weeks, revealed damage to lateral tibial nerve, tibial nerve measured amplitude, latency and conduction velocity. After electrophysiological determination of injury section of tibial nerve was cut, the use of improved Loyez's staining, each group to take any of seven vision, computational vision the number of nerve fibers, axon diameter and myelin thickness. (3) the use of SPSS 13.0 software for statistical analysis.Results: (1) general observation: 2 weeks in the experimental groups than the control group gradually visual gait. 4, the visual gait than the control group. (2) morphology: 4 weeks, the three experimental groups of nerves and surrounding tissue adhesive clear than in the control group, swelling of injured nerve in the control group significantly. (3) histologic observation: After 4 weeks, each group the number of damaged axons, myelin thickness, axon diameter of comparison: the three experimental groups were better than the control group, and the optimal ultrasound treatment group, frequency electrical stimulation Group Secondly, again the IR treatment group (P <0.05). (3) electrophysiological testing: tibial nerve damage by measuring the amplitude, latency and conduction velocity, ultrasound group showed neurological recovery was the best, better than the infrared frequency electrical stimulation treatment group, the recovery of the experimental groups were significantly better than the control group (P <0.05), consistent with the histological results.Conclusions: (1) the three physical therapy can significantly promote the regeneration of peripheral nerve damage, which may be related to three kinds of physical therapy can promote the local microcirculation in the damaged parts. (2) experiments show that regeneration of damaged nerves to promote the role of ultrasound therapy is better than frequency electrical stimulation, and the effect of infrared therapy over the first two are quite different. (3) physical therapy for injured peripheral nerve was stimulated in shortening the treatment time, and both treatment convenience, security, painless, inexpensive and is worth to promote the clinical application. |
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