Analysis On Risk Factors Of Portal Vein Thrombosis After Splenectomy With Ericardial Evascularization In Patients With Portal Hypertension

ObjectiveThe purpose of this study was to investigate the risk factors of portal vein thrombosis after splenectomy with pericardial devascularization in the patients with portal hypertension.Methods52 hospitalized patients with thrombosis complicating portal hypertension were selected and all these cases were divided into 2 groups according to portal vein thrombosis or not. The portal vein thrombosis group has 10 cases and non-portal vein thrombosis group has 42 cases. Postoperative evaluations including age, gender, and some other factors were recorded and reviewed.Resultslogistic regression analysis showed that platelet disorder and anticoagulation therapy have a close relationship with the development of PVT (P<0.05). The age, gender, and the other factors did not show significant effect on the occurrence of PVT (P>0.05).ConclusionPlatelet disorder is an independent risk factor of portal vein thrombosis after splenectomy in the patients with portal hypertension. Anticoagulation therapy given in the early stage can prevent the occurrence of the portal systerm thrombosis.