The Hemodynamic Study Of Allotype Artery By Finite Element Method

Numerical simulation of hemodynamic visualization technology has been widely used in the study of the etiological factor and pathogenesis of cardiovascular disease. Its main purpose is using the computational fluid dynamics method, by controlling the body's physiological factors of initial and boundary,to calculate and display the distribution of valuable hemodynamic features,and Analysis and discuss the mechanical interaction between changes of distribution and vasculopathy.In this thesis, making use of finite element analysis software comsol multiphysics to complete the hemodynamic visual numerical simulation,which based on the 3D geometric model of carotid artery established Solidworks and Mimics.Give a detailed description of the computational fluid dynamics methods in the application of hemodynamic study and a systematic introduction of the technical processes and the research status of hemodynamic visualization simulation.To establish the simplified models in a statistical significant of the normal, narrow and inflated carotid bifurcation, and use these models to complete the simulations and contrastive analysis,in order to discuss the effects caused by the changes of local hemodynamic factors during the occurrence and development mechanism of vasculopathy caused by atherosclerosis. Make the results compare with the existing theory and results of related literature reports, verify the feasibility and effectiveness of the numerical simulation method, and provide the heoretical basis for clinical prevention and treatment of cardiovascular disease.Constitutive Relation of blood and properties of vessel wall are two assumptions in the numerical simulation of hemodynamics. On the premise of closing the real human physiological environment, study the effects of different the assumptions in the simulation and discuss the rationality of simplification for these assumptions.Using a real individual model,which was reconstructed based on the CT medical imaging data, to check the former studies. And compare and analyze the individual specificity of hemodynamics factors in the carotid bifurcation, in order to provide more effective supports for targeting clinical diagnosis and treatment.