Clinical Therapeutic Effect Of Photodynamic Therapy And Transpupillary Thermotherapy On Circumscribed Choroidal Hemangioma

Objectiveobserve the clinical therapeutic effect of photodynamic therapy(PDT)and transpupillary thermotherapy(TTT)on circumscribed choroid hemangioma (CCH).We had 12 cases of CCH in this study.Six of them had undergone TTT, and the other six were treated by PDT using verteporfin. Best corrected visual acuity, and results of fundus photography,direct ophthalmoscopy, B-ultrasound examination, coloured doppler imaging, fluorescence fundus angiography(FFA), indocyanine green angiography(ICGA) and optical coherence tomography(OCT) were exammined and analyzed.ResultsIn all cases, the tumors shrinked back, the blood flows tuned negative,the fluorescence leakages lessened and the serous retinal detachments resolved completely according to OCT,FFA,ICGA and coloured doppler imaging.In the six patients treated by TTT, visual acuity improved in 33.3%, unchanged in 33.3%,and droped in 33.3%too; the results of fundus examinations showed obvious pigmentation and atrophy tumor with organized scar.In the six patients treated by PDT, visual acuity improved in 66.7%, unchanged in 33.3%, and none droped; the results of fundus examinations showed slight pigment derangement, atrophy tumor tuned white,and normal blood vessel undamaged. ConclutionsBoth TTT and PDT can make the tumor atrophy and the exudation absorbed. Unlike TTT, PDT damages little normal tissue, and has higher security.