| ObjectiveBy randomized controlled method, The aim of this study was to objectively evaluate the clinical effect and safety of ginger-separated moxibustion for knee osteoarthritis(KOA).Methods80 Patients with knee osteoarthritis from TaiWan Kaohsiung Liu Junliang's Chinese Clinical were recruited as research objects. They were randomly divided into test group and control group in the ratio of 1:1,40 cases each. Test group was treated with ginger-separated moxibustion combined with Chinese medicine (Strong Osteoarticular Pill) and the control group was treated with warm needling moxibustion combined with Chinese medicine (Strong Osteoarticular Pill). Acupoints Selecting:Nei Xiyan, Wai Xiyan, SP9, GB34. Acupoint Location:according to the People's Republic of China "Acupunture points positioning" standard issued by State Bureau of Technical Supervision. Chinese medicine:Strong Osteoarticular Pill, GuangCi Tang (produced by Shanghai TongHanChun Herbs Factory), for oral use, once 3 pills,3 times a day and taking successively for 30 days. Tools Selecting:needle:No.28 needle (Hua Tuo Brand). Moxa stick:pure moxa stick (Gusu Brand).Operating method:warming needling moxibustion:cut the pure moxi stick into moxa cones about 1.5cm in length each and put them on the needle handle. During moxa time, the patients would have warm feeling or burning sensation. Moxibustion for 20 minutes, so that the sense of warmth would penetrate into the knees, even obviously hot feeling inside. Ginger-separated moxibustion: cut fresh ginger into 2-3 cm in diameter, thickness of 0.2-0.3 cm, prick 10 holes the Ginger's middle, put ginger on the acupoints, the above with self-made moxa cone (weight 2g),5 cones at each point, keep skin ruddy and but not blistering. Course of treatment:once every other day,15 times as a course of treatment.observed indicators:the main symptoms of joint pain (visual analog pain scale table, VAS), assessment of knee osteoarthritis severity index (ISOA) and safety, measure all indicators for once before and after treatment. After the treatment, assess the clinical efficacy.Statistical methods:use Epi Data3.01 software for statistical analysis. Statistical method:categorical data by Chi-Square test, ranked data by two-samples compared Wilcoxon rank sum test, comparing means of two samples by T-test or Wilcoxon rank sum test, before and after itself by paired-samples T-test or Wilcoxon paired rank sum test, use statistical software SPSS17.0 to complete statistical analysis. Make use of statistical graphics software Graph Pad Prism 4.03 to complete statistical graph.ResultThe results were as follows:1. Clinical therapeutic effect:test group, clinical curative rate was 40%, markedly effective rate was 35.0%, effective rate was 17.5%, total effective rate was 92.5%; control group, clinical curative rate was 35.0%, markedly effective rate was 42.5%, effective rate was 7.5%, total effective rate was 85.0%. The clinical efficacy and the total effective rate analyzed by rank sum test and chi-square test respectively, the differences were not statistically significant (P> 0.05). Clinical curative rate and total effective rate of test group were higher than that of control group after treatment, but there was no difference between the two groups (P> 0.05).2. VAS score:the mean±standard deviation of VAS score was 7.36±2.31 in test group and 7.15±2.19 in control group before treatment and decreased to 3.42±1.73 and 3.67±1.47 respectively after treatment, meaning that pain was lightened significantly and the difference was statistically significant (P<0.01). From the change of mean±standard 4.03±1.22 and 3.50±1.24 in the two groups after treatment, we can see that ginger-separated moxibustion is more significant in relieving pain, but difference was not statistically significant(P>0.05), indicating that ginger-seperated moxibustion and warm needling moxibustion can significantly relieve pain.3. Knee osteoarthritis severity index(ISOA):test group and control group effectively reduced the accumulated scores of pain, walking and life. Total scores were 19.04±4.37 in test groep and 18.92±4.26 in another before treatment and decreased to 6.58±2.29 and 7.54±2.45 respectively after treatment. By paired-sample t test, there was statistically significant difference (P<0.01) in accumulated scores between the two group. The change of mean±standard 12.46±3.42 in test group, was larger than that 10.83±2.96 in the control group. By two sample t test, there was statistically significant differences(P<0.05), showing that ginger-separated moxibustion and warm needling moxibustion can effectively relieve pain and restore joint function, but Ginger-separated moxibustion has a better effect.During treatment no adverse reaction was found in the two groups.ConclusionThe therapy of ginger-separated moxibustion and warm needling moxibustion for knee osteoarthritis had similar effect on clinical efficacy and improvement of accumulated scores. Ginger-separated moxibustion can effectively control or mitigate the development of knee osteoarthritis and improve patients'quality of life. It is a safe and effective therapy, with convenience of materials obtaining and low price, which is easily to be learned and deserves promotion. |
PDF Full Text Request