Research On Efficacy Of Acute Bronchial Asthma With The Jiawei Maxingganshi Decoction

Bronchial asthma is a chronic inflammatory airway disease which involved in a variety of cells including airway inflammatory cells and structural cells (such as eosinophils, mast cells, T lymphocytes, neutrophils, smooth muscle cells, airway epithelial cells) and cellular components (cellular elements). Such chronic inflammation leads to airway hyperresponsiveness, usually wide and varied reversible airflow limitation, and cause repeated episodes of wheezing, shortness of breath, chest tightness or cough, it often attack at night and (or) early morning, intensified many of the patients and relieve itself or remission. The treatment of asthma, Western currently mostly used glucocorticoid,β2 adrenergic agonists, but long-term inhaled steroid, often hoarseness, dysphagia, mouth ulcers and other side effects.In Chinese Traditional Medicine, because old tan in lung meets motivation, obstructs airway, makes airway spasm, lung cannot evaporate or astringe, the qi of lung superinverses and makes wheezy phlegm and breathlessness, even patient cannot lay down. Chinese Medicine have treated asthma and other respiratory diseases well for long, made less side-effects and cost less, so extending Chinese Medicine will bring important sense in clinic. To evaluate the effect and side-effects of Jiaweimaxingganshi Decotion, this study was carried on. Methods50 patients meeting the criterion randomly divided into the treatment group and the control group. The treatment group with Jiaweimaxingganshi Decoction integrated Western medicine, the control group with Western medicine only were observed one week, the change of clinical symptoms, such as wheezy, cough, stethocatharsis, chest distress, Dry mouth, wheezing rale, and laboratory indexes, such as eosinophile granulocyte(EOS), immune globulin E(IgE), endothelin(ET) was observed between before and after treatment.Results1 Symptoms of two groups are different after treatment while comparing with themselves, symptoms such as wheezy and dry mouth show different between these two groups.2 After therapy, EOS of two groups decrease, and it's conspicuously different, but between these two groups there is no difference.3 After therapy, IgE of two groups decrease, and it's expressly different, but between these two groups there is no difference.4 ET of two groups decrease, and it's conspicuously different, and between these two groups there is conspicuously difference.ConcludeJiaweimaxingganshi Decoction and Western medicine used together could expressly ameliorate symptoms of patients at acute episode, decrease laboratory indexes such as EOS, IgE, ET, and extenuate airway hyper reactivity, improve clinical effect, and is worth for generalization.