| Objective:Our study is to summarize the characteristic of TCM determination of treatment based in pathogenesis obtained through differentiation of symptoms and signs and western medicine therapeutics by information of rheumatoid arthritis patients, and know the history regularity further, so can give proof to better treatment.Methods:To evaluate the clinical efficacy of Erteng Tongbi Mixture combined with rehabilitation gymnastics on Treating Ankylosing Spondilitis. Method:Choose sixty examples which accorded with standardment of AS, divide them into two groups ranmdomly. Therapy group treated by Erteng Tongbi Mixture combined with rehabilitation gymnastics, take 20ml once, three times a day, combined with rehabilitation gymnastics, which is followed with the《The instructions of rehabilitation gymnastics》,treat for three months;control group treated by Erteng Tongbi Mixture, take 20ml once, three times a day, treat for three months. To observe the clinical symptoms such as BASDAI,BASFI score, PGV score, peripheral index number of arthrosis swell,activity of thoracic skeleton, activity of the spongdy, after four weeks, eight weeks, twelve weeks;to observe the lab result such as the CRP, ESR after twelve weeks treatment, to monitor blood routine, the function of liver and kidney.Results:Therapy group:After four weeks treatment,comared to the original level, body function, rachialgia, stiffness of spondy, total self-assessment, peripheral swelling arthrosis,activity of thoracic skeleton, Schober test, distance between fingers and ground, antisernum hypsokinesis were improved significantly(P<0.05);distance between head and wall, side flection of antisternum were not improved significantly(P>0.05). After eight weeks and twelve weeks treatment, compared to the original level, body function, rachialgia, stiffness of spondy, total self-assessment, peripheral swelling arthrosis, activity of thoracic skeleton, Schober test, distance between fingers and ground, distance between head and wall, side flection of antisternum, antisernum hypsokinesis were improved significantly(P<0.05).Conclusion:After four weeks treatment, compared to the original level, rachialgia, total self-assessment, peripheral swelling arthrosis were improved significantly(P<0.05).body function, stiffness of spondy, activity of thoracic skeleton, Schober test, distance between fingers and ground, distance between head and wall, side flection of antisternum, antisernum hypsokinesis were not improved significantly(P>0.05). After eight weeks and twelve weeks treatment, compared to the original level, body function, rachialgia, stiffness of spondy, total self-assessment, peripheral swelling arthrosis, activity of thoracic skeleton, Schober test, distance between fingers and ground, side flection of antisternum, antisernum hypsokiolnesis were improved significantly(P<0.05); distance between head and wall were not improved significantly(P>0.05). Therapy group VS control group:After eight weeks treatment, there was difference in body function, stiffness of spondy, peripheral swelling arthrosis, activity of thoracic skeleton, Schober test, distance between fingers and ground, antisernum hypsokinesis between them(P<0.05). After twelve weeks treatment, there was difference in body function, rachialgia, stiffness of spondy, total self-assessment, peripheral swelling arthrosis, activity of thoracic skeleton, Schober test, distance between fingers and ground, distance between head and wall, antisernum hypsokinesis between them(P<0.05).After twelve weeks treatment, compared to original level,the CRP and ESR were improved significantly in both groups(P<0.05). The CRP of therapy group was improved significantly than control group(P<0.05).Conclusion:Erteng Tongbi Mixture combined with rehabilitation gymnastics has the certain therapeutic effect of treating AS. And the therapeutic effect of Erteng Tongbi Mixture combined with rehabilitation gymnastics surpasses the therapeutic effect of Erteng Tongbi Mixture. |