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A Study Of Biocompatibility Of Multi-wall Carbon Nanotube

Posted on:2011-03-31Degree:MasterType:Thesis
Country:ChinaCandidate:L YuanFull Text:PDF
GTID:2144360305968028Subject:Condensed matter physics
Abstract/Summary:PDF Full Text Request
Nanotechnology is the 20th century, late 80s, early 90s was gradually developed in the forefront of a new cross-disciplinary field, Its rapid development will be activated in the 21st century, all industrial sectors to promote a revolutionary change. Since the discovery of carbon nanotubes (CNTs) has been, CNTs on with its excellent electrical conductivity, mechanical and semiconductor properties of the field of materials science and become a star, has a wide range of applications and commercial value. The study that the CNTs biocompatible better, so its biomedical materials have great application value.Bio-medical applications, currently targeted research mainly involves surface modification of carbon nanotubes, it has to prevent non-specific adsorption of proteins and identification of specific protein molecules in the function; the use of carbon nanotube electrical properties of the particular shape and to study the cell The in vitro growth and so on. This paper studied the carbon nanotubes (MWCNTs) surface of hemolysis, platelet adhesion and blood protein adsorption as well as cells in the material on the adhesion and growth behavior. The results showed that: Nitrogen-doped and non-nitrogen-doped multi-walled carbon nanotube materials for cell provides a natural extracellular matrix near the built environment, has significantly promoted the proliferation of cell adhesion and long features, with good cell compatibility. Despite the multi-walled carbon nanotubes and carbon paper two kinds of surface adsorption of albumin (Albumin, Alb) as does the size carbon paper adsorption of fibrinogen (Fibrinogen, Fib) and immunoglobulin (Immunoglobulin, IgG) to be less than the multi-walled carbon nanotubes, but multi-walled carbon nanotubes in hemolytic rate and platelet adhesion rate to be lower than the carbon paper, which means that the relatively hydrophobic carbon paper in terms of better multi-walled carbon nanotubes may inhibit platelet adhesion and The formation of thrombus more capable in the carbon paper, with a certain degree of blood compatibility. The results show that the multi-walled carbon nanotubes have the physical and chemical properties of biological materials should possess high strength, low modulus, corrosion-resistant characteristics, but also has good biocompatibility, the present multi-walled carbon nanotube material in the future bio-medical and new materials have potential application value of these findings for future deeper study provides the experimental basis and useful scientific data.
Keywords/Search Tags:multi-walled carbon nanotubes, cell adhesion, blood protein adsorption, hemolysis, platelet, biocompatibility
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