On-line Detection Of The Diffusion Rate Of Water-soluble Components From Salvia Miltiorrhiza Bge

As a commonly used herbs, Salvia Miltiorrhiza Bge has a long history in traditional Chinese medicine. Modern medical studies indicate that the water-soluble components of Salvia Miltiorrhiza Bge has good effects on promoting blood flow and regulating menstruation. On-line detection of the extraction of water-soluble components from Salvia can result in high quality of the liquid medicine.The rate of infusion of water-soluble components from Salvia miltiorrihiza Bge was measured online with OceanOptics spectrometer-HR2000. The solid-to-liquid ratio is 2g:250ml when the spectrometer is directly used for detection. The effects of temperature, particle size and water-soak to the extract process were analyzed respectively. The fractions in the ranges 2-5mm,0.7-2mm,0.3-0.7mm were chosen. The rate of infusion was found to increase greatly with increasing water temperature or decreasing particle size. It showed little variation with the dip-treatment. The kinetic model has been built base on Fick's second law and the data of the experiments meet the equation very well. Using particles of size 2-5mm, the rate of infusion was measured over 30-90℃. The activation energy was found to be 24.1KJ.mol-1. Finally, the use of spectrometer in practice is discussed based on its advantages.