Ningxin Annao Decoction For Treatment Of Sub-health State With Insomnia Of Deficiency Syndrome Of Heart And Kidney

Objective Ning Anshen Treatment of brain heart and kidney deficiency type insomnia sub clinical efficacy.Method1. General Information All cases were from 2009.5-2010.10 treatment in Traditional Chinese Medicine, Second Hospital of Shanxi Medical University, the insomnia patients selected 60 patients met the inclusion criteria, of which 38 males and 22 females; aged 35-60 years; course of 6 months to 2 years. Randomly divided into two groups, treatment group, 30 cases 20 males and 10 females; aged 35-60 years, mean (45.56±2.78) years; course of 6 months to 2 years, the average (13.58±2.52) months; sleep Quality PSQI score (12.45±1.89) points. Control group of 30 patients 18 males and 12 females; aged 35-60 years, mean (44.33±2.38) years; course of 6 months to 2 years, the average (14.28±1.89) months; PSQI sleep quality score (12.36±1.78 ) points. Two groups in gender, age, duration of disease, illness, etc. no significant difference (P> 0.05), comparable.2. Treatment30 patients treated using Ningxin Annao Decoction Treatment of brain, base side: Rehmannia 30g, cornus 30g, Radix 15g, Schisandra 15g, Fu Shen 15g, angelica 15g, fried Zaoren 30g, Polygala 15g, Health keel 30g, Salvia 15g, tangerine peel 12g, threatened with chest expansion, could add Albizia julibrissin 12 g, the system Cyperus rotundus 12 g; with looking Shaohua, Shenpi fatigue, loss of appetite, Astragalus 15 g, longan meat, 15 g; with red urinate , bamboo can be added 6 g, rush 1.5 g; upset, insomnia, restless person, Zhuojia Coptis 3 g, cinnamon 2 g. A day, morning and evening hours service;Control group of 30 patients to oral Zopiclone tablets (Jilin Henghe Co., Ltd. production, Zhunzi H19991411) treatment, 7.5mg orally at bedtime, day 1.The treatment lasted 4 weeks. All patients taking other sedative drugs during the disabled, avoid tea, coffee, spicy food stimulation, the treatment of sleep hygiene education also have to improve their sleep habits and lifestyle.Results The main outcome measures were the overall clinical efficacy and the two groups recently assessed quality of sleep.Reference to the overall clinical efficacy, "the guiding principles of Chinese medicine clinical research new drugs" in efficacy evaluation, treatment group, total effective rate was 83.33% in the control group total effective rate was 80.00%, which showed no significant difference (P> 0.05) , the same treatment group than the control group; Recent sleep quality was assessed using internationally accepted reflect the quality of sleep in Pittsburgh Sleep Quality Index (Pittsburgh sleep quality index, PSQI) on the last 1 month in patients with sleep quality were assessed, the intervention group and control group PSQl total score was 10.65±2.56 and 11.46±1.66, significantly decreased (compared with the group before treatment, P <0.05, statistically significant), but showed no significant difference (P> 0.05).Conclusions Ningxin Annao Decoction side can improve sub-health state of patients with heart and kidney deficiency type insomnia sleep quality, total effective rate was 83.33%, and the new non-benzodiazepine drugs Zopiclone tablets with the same therapeutic effect, short-term clinical results were satisfactory . But the effect of short-term improvement in patients with insomnia than Western zopiclone tablets, and in improving sub-health status of patients is superior to the other side.