The Differentiation Value Of High-grade Gliomas And Primary Intracranial Lymphomas In Susceptibility-weighted Imaging (SWI)

Objective: To analyse the susceptibility-weighted imaging (SWI) findings of high-grade gliomas and primary intracranial lymphomas,and to evaluate the value of differential diagnosis between these two tumors by SWI. Materials and Methods:In the study,T1WI,T2WI,DWI and SWI on a 3.0 T scanner (SIEMENS Verio 3.0T) were performed preoperatively in 27 patients with high-grade gliomas(a total of 42 lesions)and 12 patients with primary intracranial lymphomas(a total of 26 lesions)which were confirmed by pathological examination. Expect a patient with high-grade gliomas,all the other 38 patients underwent T1WI enhancement scanning. The number of lesions which were found hemorrhage on the conventional MR imaging and SWI were counted,then the detection rates on SWI and the conventional MR imaging were statistically analyzed in two tumors,and the hemorrhage rate of these two tumors on SWI was also statistically analyzed. Futhermore, the volume of hemorrhage and the number of the vessels in lesions of these two tumors were statistically analyzed.Result:On the conventional MR imaging, hemorrhage was found in 6 lesions of high-grade gliomas and 2 lesions of primary intracranial lymphomas. On SWI, hemorrhage was found in 30 lesions of high-grade gliomas and 3 lesions of primary intracranial lymphomas. There was a statistically significant difference in the detection of hemorrhage between the conventional MR imaging and SWI (P<0.05) in high-grade gliomas, but not in primary intracranial lymphomas (P>0.05). There was a statistically significant difference in the hemorrhage rates of these two tumors on SWI (P<0.05). On SWI, in high-grade gliomas, hemorrhage which was recorded as 1 point were found in 11 lesions, hemorrhage which was recorded as 2 points were found in 19 lesions, the number of intratumoral vessels which was recorded as 1 point were found in 8 lesions,2 points were found in 21 lesions. In primary intracranial lymphomas,hemorrhage which was recorded as 1 point were found in only 3 lesions and no vessels were found in all the lesions. Among these two tumors, the statistically significant differences were found in the volume of hemorrhage and the number of the vessels in lesions (P<0.05). Conclusion:SWI is more sensitive than the conventional MR imaging in diagnosing hemorrhage of high-grade gliomas. On SWI, the hemorrhage rate, the volume of hemorrhage and the number of the vessels in lesions of high-grade gliomas are higher than primary intracranial lymphomas. Therefore, SWI can be helpful in the differentiation of and primary intracranial lymphomas.