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HBV Infection Distribution And It's Risk Factors In The Employees Of Food And Public Health Service In Pujiang County

Posted on:2012-08-16Degree:MasterType:Thesis
Country:ChinaCandidate:Z P YouFull Text:PDF
GTID:2154330335993490Subject:Epidemiology and Health Statistics
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Background:Hepatitis B is a global disease that caused by the hepatitis B virus (HBV). Hepatitis B is the most serious human health hazards in the five types of viral hepatitis. The prevalence of hepatitis B has become a major public health problem in China. The 2006 survey shows that the hepatitis B infection declined, but there were still up 7.18% HBsAg carriers. Despite of the strict control of blood and iatrogenic transmission, reported incidence rates of hepatitis B go steadily up in Pujiang County in recent years. Speculated that there must be other risk factors at work. We can not ignore that the HBV infection of special employees impacts on society health, although the hepatitis B test is abolished.Objective:The objective of the paper is to find out the infection situation of catering trade and public places employees who infected with hepatitis B and to learn the distribution of risk factors in Pujiang County. Furthermore, to study validation of traditional risk factors and to explored whether there are specific risk factors in practitioners. The paper will provide a reference of hepatitis B prevention and control strategies after the abolition of hepatitis B test in practitioners. Methods:By organizing data on food and public places employees in Pujiang County in 2009, there is a descriptive epidemiological study on collecting the total number of physical, HBsAg positive number, the number of HBsAg HBeAg HBcAb positive and HbsAg HBeAb HBcAb positive, the number of healthy people and the number of other indicators. It take HBsAg-positive as an indicator of hepatitis B infection and take 200 randomly selected people from the B influenza infection as the case, take 200 healthy people as controls. Case-control study conducted in groups. There is no significant difference in composition among control group and patient group in gender and age. Some qualified home inspectors investigated sociological characteristics, immunization history, family infection, daily living habits etc. The questionnaire was gathered on the spot. Lost to follow-up object consists of system sampling 200 outside object complement. All cases with Epidata3.1 establish unified coding, database, using SPSS 16.0 statistical software package for statistical data analysis. Single-factor analysis compared each possible risk factor and hepatitis B infection and screened variable initially, then use the stepwise regression for multivariate non-conditional logistic regression analysis.Results:From the examination of the 6878 food and public places employees in Pujiang County in 2009, we may find there are 435 HBsAg-positive persons, the positive rate was 6.32%,3398 were males, the positive rate was 6.95%,3480 were women, the positive rate was 5.72%. Differences between male and female infection rate was significant (χ2=4.368,P<0.05).There are 435 hepatitis B infection, the three positive largest, a total of 258, accounting for 59.31% of all infected persons, followed by three positive infection, accounting for 15.63%. The minimum age is 18 in infected employees, the oldest is 60. Take 10 years as an age division,30 years old is the highest infection group. However, no significant difference in infection rates in all age groups. In case of family members of Hepatitis B infection, there are 43.8% in the case group of mothers. The rate is 37.1% in the control group of fathers. After univariate analysis, family members of hepatitis B patients, dental treatment history, dining out, sharing toothbrushes and other daily necessities, traumatic beauty, often flows went into the risk factors of hepatitis B infection. Taking hepatitis B vaccine is a protective factor (χ2=28.108, P<0.01). Single factor selected risk factors and vaccination and drinking liquor. After using the method of stepwise multivariate logistic regression analysis, we can find family members of hepatitis B patients, dental treatment history, eating out, often flow, vaccination went into the equation, the OR values were 3.548,2.978,4.675,4.492,0.143.Conclusion:Through the data of 6878 food and public places employees in Pujiang County in 2009, we can find the positive rate of HBsAg (HBV infection) is 6.32%, lower than the prevalence of hepatitis B of different groups of people in Jinhua City. HBsAg positive rate of male employees was higher than female employees, but all ages HBV infection was no significant difference. Univariate analysis showed that the possible risk factors for hepatitis B infection are:family members of hepatitis B infection, dental surgery, sharing cups and other household items, dining out frequently, traumatic beauty, often flow. Multivariate analysis showed that family members of hepatitis B infection, dental surgery, regular flow and eating out is the main risk factors for hepatitis B infection and taking hepatitis B vaccination is a protective factor.
Keywords/Search Tags:Employees, hepatitis B infection, case-control, risk factors
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