Investigate The Correlation Between The Residual Renal Function And Cardiovascular Disease In Peritoneal Dialysis Patients

Objective: To investigate the relationship between the residual renal function (RRF) and left ventricle mass(LVMASS)in peritoneal dialysis patients. Methods: In a cross-sectional study, 103 patients treated with peritoneal dialysis for at least 6 months were investigated.①Patients were divided into three groups according to their RRF. The group A(RRF0-2ml/min)31 cases,group B(2ml/min4ml/min)30 cases.②Patients were divided into two groups according to their protopathy. The group Diabetic Nephropathy 40 cases, group Non- Diabetic Nephropathy 63 case. Patient's glomerular filtration rate(GFR), blood pressure, serum parathormone concentration, serum calcium and phosphonium concentration were investigated. Patient's left ventricle weight and left ventricular mass index were assessed by ultrasonic cardiogram. Results:①There were no significant differences in the age, stature, body weight, Mean arterial pressure and serum calcium concentration between the three groups.②Compared with group A, the Serum phosphonium, multiplication of calcium and phosphorus, iPTH, LVW and LVMI were significantly lower in group B and C (P﹤0.01).③By Pearson relative analysis, Serum phosphonium, multiplication of calcium and phosphorus and iPTH were significantly negative correlated with GFR. Meanwhile, the mean arterial pressure, Serum phosphonium, multiplication of calcium and phosphorus and iPTH were significantly positive correlated with LVW and LVM.④Compared with group of Diabetic Nephropathy, the residual renal function ,serum calcium and LVW and LVMI were lower in group Non- Diabetic Nephropathy. To the contrary, Mean arterial pressure, the Serum phosphonium, multiplication of calcium and phosphorus and iPTH were higher in group Non- Diabetic Nephropathy. Conclusion: Our data showed that the strong relationship between the losing of residual renal function and the declining in left ventricle mass(LVMASS). Portecting the residual renal function positivly can reduce the incidence rate of cardiovascular disease and the mortality rate in peritoneal dialysis patients. Compared with group Non-Diabetic Nephropathy, starting dialysis were earlyer, left ventricular weight were lighter and have more residual renal function in group Diabetic Nephropathy. Objective: To investigate the influence of left ventricle mass after control blood pressure and correct calcium phosphate metabolic disorder in peritoneal dialysis patients. Methods: On the base of cross-sectional study investigation, 103 patients treated with peritoneal dialysis actively give control of blood pressure and correcting calcium phosphate metabolic disorder and hyperparathyroidism treatment until 2009 December. Material complete cases were 37 cases. Patient's blood pressure, serum calcium, serum parathormone concentration, serum calcium and phosphonium concentration, serum creatinine, height, weight, left ventricle weight and left ventricular mass index were investigated after controlling of blood pressure and correcting calcium phosphate metabolic disorder treatment seven months. Results: Compared with befor treatment, mean arterial pressure, serum phosphate concentration, serum calcium and phosphonium concentration, parathyroid hormone, left ventricular weight and left ventricular weight index were significantly lower instead serum calcium were significantly higher after treatment, P<0.05. Conclusion: Positive treatment of blood pressure, calcium phosphate metabolic disorder and hyperparathyroidism can reduce cardiovascular disease incidence and mortality in peritoneal dialysis patients.