Clinical Research On The Features Of TCM Constitution In Patients With Nonalcoholic Fatty Liver Disease

Objective:To use the epidemiological methods for analyzing the distribution of TCM constitution types in patient with Non-acoholic Fatty Liver Disease(NAFLD), and the relationship between TCM constitution with age, gender, body mass index (BMI), laboratory tests and syndrome differentiation. To explore the internal relationship and regular between TCM constitution and NAFLD, providing a theoretic foundation for study of TCM constitution, which can be a new way to prevent and treat NAFLD.Methods:With a method of combining literature and clinical research.,150 patients of NAFLD are chosen to take a question investigation. All the data is recorded in Excel table, processed by SPSS statistical software to analyze the relationship between TCM constitution and age, gender, BMI, laboratory tests and syndrome types.Results:To compare the mean scores of patho-constitution types, phlegm-dampness type gets the highest(33.61±12.47), followed by qi-deficiency type(30.88±11.21)and dampness-heat type(30.17±12.03), which indicates that the three types of TCM Constitution are most obviously physical tendencies. Comparison of the frequency of TCM Constitution shows that, phlegm-dampness, qi-deficiency and dampness-heat type are more than other types. Analyzed from age factor, as age grows, the scores of qi-deficiency and blood-stasis type increase while dampness-heat decrease. Phlegm-dampness type is most obvious expressed by patients of Mid-age. Analyzed from gender factor, male gets higher score than female in dampness-heat while female gets higher than male in qi-deficiency, yang-deficiency and blood-stasis types. Analyzed by BMI, patients of over weight get high score of phlegm-dampness. Analyzed by laboratory tests, patients with liver disfunction, hyperlipidemia, hypertension and hyperglycemia get more points in phlegm-dampness type. No obvious regular is found between the relationship of NAFLD patient's syndrome differentiation types and constitution types.Conclusion:Phlegm-dampness, qi-deficiency and dampness-heat types, are the main constitution of TCM in patients with NAFLD. These three pathological factors are closely connected with the occurrence of NAFLD. Of all these factors, phlegm-dampness type is the most important for the occurrence of NAFLD. Patients with fatness, hyperlipidema, hyperglycemia or hypertension gain higher points of phlegm-dampness than other patho-constitution. It suggests to achieve a better clinical treating effect and keep healthy, we should correct the pathological situation according to a completely analysis of body constitution, syndrome differentiation and the disease.