Correlational Study On Traditional Chinese Medicine(TCM) Syndrome Differentiation-Type Of Hyperthyroidism, Bone Mineral Density And Bone Metabolic Markers

Objective:Detection bone mineral density(BMD),osteocalcin (BGP,serum 0-1 type I collagen C-terminal peptide(β-CTx) of Traditional Chinese Medicine(TCM) Syndrome Differentiation-Type in patients with hyperthyroidism and some bone metabolic markers, and to explore the relationships between TCM Syndrome ifferentiation-Type of hyperthyroidism, bone mineral density and bone metabolic markers,and to seek the difference of potential risk about TCM Syndrome ifferentiation-Type of hyperthyroidism induced-osteoporosis, and for preventing a new idea with early provision and treatment of hyperthyroidism accompanied by osteoporosis.Methods:111 patients who are diagnosed with hyperthyroidism adopting the standard of selection.was screened for general conditions,and divided into four groups according to TCM Syndrome-type standard:A group (qi Phlegm group),B group (sputum knot blood stasis group),C group (anger strong group), D group (heart and liver Yin deficiency group).All cases were detected bone mineral density (BMD) (including the femoral neck, greater trochanter, Wards triangle, L2-L4), osteocalcin (BGP), and serumβ-1 typeⅠcollagen C-terminal peptide (β-CTx).We compared the differences about these data in each group,and then analyzed the relationship among TCM patterns of hyperthyroidism,BMD,BGP andβ-CTx.Results:1.In sex, age, height, weight and duration of the comparison results had no effect (P>0.05) of the cases:qi Phlegm group compared with the other three groups, all parts have higher bone mineral density, and statistically significant (P<0.05); anger exuberant group compared with the other three groups, each part of bone mineral density were lower, with statistical significance (P<0.05).2. The card type group in patients with hyperthyroidism osteocalcin (BGP) detection, by the rank sum test, the difference was not statistically Italy (P> 0.05). Line 2 for further comparison, the qi Phlegm group compared with the other three groups, were statistically significant (P<0.05); phlegm and blood stasis group and anger strong knot group, heart and liver yin deficiency group, no statistical significance(P>0.05).3.Hyperthyroidism in patients with serum levels of various card-typeβ-1 typeⅠcollagen C-terminal peptide (β-CTx) detection, by the rank sum test, no statistically significant difference (P>0.05). Line 2 for further comparison, the qi Phlegm group compared with the other three groups, were statistically significant (P<0.05); phlegm and blood stasis group and anger strong knot group, heart and liver yin deficiency group, no statistical significance(P> 0.05).Conclusions:1.Hyperthyroidism in patients with qi Phlegm card, sputum knot blood stasis, anger strong card, heart and liver Yin deficiency of BMD, BGP,β-CTx differences in sex, BMD, BGP, P-CTx and TCM Syndrome Differentiation-related there is a specific sex.2. Reduced bone mineral density in hyperthyroidism in all license types are statistically significant, of which anger strong cards to reduce the extent of bone mineral density in patients with hyperthyroidism is most apparent in the clinical hyperthyroidism in patients with this type should take early measures for prevention of osteoporosis.3.Phlegm card hyperthyroidism qi reduced bone mineral density and bone metabolism in patients with the imbalance between the lowest level, so the development of osteoporosis are also the smallest of the potential danger.