| Objective:Assessment of continuous ambulatory peritoneal dialysis (CAPD) patients with depression and psychological status of peritoneal dialysis patients with depression and TCM Syndrome Differentiation in the relationship between the guidance in peritoneal dialysis patients mental health, prevention and treatment for TCM to find objective evidence of depression.Methods:1. Survey Wuhan Hospital of Integrated Chinese and Western Medicine Nephrology Peritoneal Dialysis Center in March 2009-March 2010 PD patients. Someone to collect cases,120 cases meet the standards included in this study.2. Syndrome Differentiation standards-referenced medical technology in China in 2002 published the "Guiding Principles of Chinese Medicine Clinical Research new drugs" Chronic renal failure TCM diagnostic standards.3. TCM physicians from the dialysis center completed in strict accordance with reference standard dialectic.4. All patients using the Hamilton Rating Scale for depression level, further depression diagnosis. Diagnosis of depression according to the Chinese Classification and Diagnostic Criteria of Mental Disorders CCMD-3 criteria, divided into the depression group and the non-depressed group.5. Were observed with gender, age, education, dialysis time, underlying diseases, cost and relevance of urine and depression syndromes in patients with hemoglobin, dialysis adequacy, and creatinine clearance rate of biochemical relevance.6. Data are mean±standard deviation (x±s) indicated. Comparison of measurement data using t tests compared count data using chi-square test, P＜0.05 was statistically significant, statistical software used SPSS16.0Results:1. Group of PD patients with major depressive symptoms were weak waist, dizziness, headache, lassitude, dry mouth and throat, eat less poor appetite, shortness of breath, disinclination to talk, insomnia, forgetfulness, abnormal bowel movements, pale tongue, thin pulse string; non-depression The main clinical symptoms of PD patients group were lassitude, shortness of breath, disinclination to talk, aversion to cold, eating less poor appetite, nausea, vomiting, backache knees soft, edema, abnormal bowel movements, pale tongue with scalloped, the pulse was fine.2. Deficiency of the two groups were compared:depressed patients and the spleen and kidney qi deficiency in 11 cases (18.3%), spleen deficiency syndrome in 15 cases (25%), liver kidney yin deficiency syndrome in 18 cases (30%), Qi and Yin deficiency 10 cases (16.7%), deficiency of both yin and yang, 6 cases (10%); non-depressed patients and the spleen and kidney qi deficiency in 28 cases (46.7%), spleen and kidney yang 12 cases (20%),8 cases of liver and kidney (13.3%), Qi and Yin deficiency in 7 cases (11.7%), yin and yang, five cases (8.3%). Depression of liver kidney yin deficiency syndrome were more than non-depressed group, there are differences (P＜0.05). Spleen and kidney qi deficiency of non-depressed group was more than the depression group, there are differences (P＜0.05).3. Empirical Comparison of two groups:depressed patients and the water wet card in 9 cases(15%), turbid damp in 13 cases (21.7%), dampness in 10 cases (16.7%), blood stasis in 20 cases (33.3%), wind Certificate in 8 cases (13.3%); non-water wet depression in patients 10 patients (16.7%), turbid damp in 25 cases (41.7%), dampness in 9 cases (15%), blood stasis in 9 cases (15%) Wind card in 7 cases (11.6%). Depression, blood stasis syndrome group were more than non-depressed group, there are differences(P＜0.05). Turbid damp non-depression group was more than the depression group, there are differences (P＜0.05).4. Two groups of patients with parathyroid hormone (PTH), urea clearance (KT/V) levels were not significantly different (P> 0.05); in hemoglobin (HGB), total protein(TP), albumin(ALB), creatinine clearan cerate(Ccr) levels were significantly different (P＜0.05).5. Depression group, biochemical comparison between deficiency: liver kidney yin and spleen and kidney yang, Qi-yin deficiency, yin and yang, compare the three syndromes, TP was significant difference (P all＜0.05), liver and kidney TP Yin deficiency syndrome was significantly lower than the other three; compared with spleen and kidney qi deficiency, TP was no significant difference (P＞0.05); liver kidney yin deficiency with spleen and kidney, spleen deficiency, Yin of the two virtual, yin and yang of four syndromes compared, Ccr was significant difference (Pall＜0.05), liver kidney yin Ccr was significantly lower than the other four syndromes. Between the various syndromes HGB, ALB was no significant difference (P>0.05).6. Depression group, empirical comparison between the biochemical indicators:blood stasis and water wet evidence, turbid damp, dampness, wind permits comparison of four syndromes, HGB significant difference (P all＜0.05), blood stasis HGB significantly lower than the other four syndromes; blood stasis and permit water wet, wet cloud card, Wind cards compare the three syndromes, TP was significant difference (P＜0.05), blood stasis was significantly lower than the other three TP a card-type; compared with damp, TP was no significant difference (P＞0.05); blood stasis and water wet, wet and dirty, damp, wind-driven comparison of four syndromes,Ccr was significant difference (Pall＜0.05), Ccr blood stasis syndrome was significantly lower than the other four. ALB each syndrome was no significant difference (P>0.05).Conclusion:1. Depressed patients with liver kidney yin deficiency syndrome based, evidence-based with blood stasis syndrome; non-depressed patients with deficiency of spleen and kidney qi deficiency syndrome based, empirical evidence based wet cloud.2.Depression in patients with HGB, TP, ALB, Ccr there were significant differences; in PTH, KT/V was no significant difference. 3. Liver Kidney Yin Deficiency Ccr level of depression among the lowest in the deficiency, blood stasis of depression in patients with HGB, Ccr level of the lowest in the evidence... |
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