Correlation Between Retinal Nerve Fiber Layer Detected By OCT3 And Visual Field Defect In Primary Open Angle Glaucoma

Objective: To study the stratus optical coherence tomography 3000 detection of primary open-angle glaucoma the optic nerve fiber layer thickness changes, and OCULUS Easyflied perimetry vision testing the relevance of the visual field defect, to assess value of the OCT3 detected nerve fiber layer thickness in the early diagnosis of POAG. Methods: 34 cases (68 eyes) with normal, 37 patients (68 eyes) with suspected open-angle glaucoma, 37 patients (68 eyes) with primary open-angle glaucoma, using OCULUS Easyflied perimetry and OCT3 respectively the mean deviation of vision defects and optic nerve fibers thickness testing. The differences of the retinal nerve fiber layer detected by OCT3 among these three groups were compared and the correlation between mean deviation and retinal nerve fiber layer in glaucomatous eyes were also analyzed. Results: OCT3 detected in normal group, SOAG, POAG of three groups of any two of the optic nerve fiber layer thickness, in addition to the normal group and SOAG Tavg was no significant difference (P = 0.072), the more than three groups of pairwise comparison between the existence of all values are significantly different (P>0.05). Avg. Thi, Iavg and Savg had the better correlation with MD in POAG (P<0.01), Tavg correlation with the MD followed by (P = 0.010), Navg than the correlation with the MD difference (P = 0.052). Conclusion: Measurement of retinal nerve fiber layer by OCT3 is useful indetecting early glaucomatous damage and has marked correlation with MD, and OCT3 measurement of retinal nerve fiber layer may provide clinically relevant in formation in monitioring glaucomatous changes. The OCT3 measurement of retinal nerve fiber layer is of great value to diagnosis of POAG.