| ObjectTo investigate the clinical and vaginal microecology features in women with bacterial vaginosis (BV).MethodsFrom October 2008 to September 2009, 220 cases with health women and 380 cases with BV diagnosed by Amsel criteria were studied. The vaginal secretions were grouped by Nugent scoring system, examined by Gram stain inspection of vaginal bacteria and microecology appraisal. Ureaplasma urealyticum, Mycoplasma hominis, Chlamydia trachomatis, fungal cultures and identification were tested.Results50.79% of BV was found with fishy odor vaginal discharge, 33.42% was found with increased vaginal discharge. 74.47% was found with a thin and homogeneous discharge. 93.95% was found with vaginal pH>4.5 and 100% was found with clue cell positive. The diagnostic sensitivity and specificity of Nugent scoring system compared with Amsel criteria was 71.84% and 100%. Among 600 cases, 214 cases were identified as normal vaginal microecology, 113 cases were intermediate and 273 cases were BV by Nugent scoring system. 296.70% (64/273) of BV group vaginal flora was predominated by Gardnerella vaginalis with the deficiency of lactobacillus. The population density and multiplicity was increased except the quantity of leukocyte. U.urealyticum was isolated in 76.19% of BV group, 69.03% in intermediate group and 59.81% in normal group. M.hominis was isolated in 41.76%, 21.24% and 18.69% respectively. C.trachomatis was isolated in 5.86%, 1.77% and 0.93% respectively. There were statistical differences in the isolation rates. The prevalence of recurrent BV was 2.63% (10/380).ConclusionThe main clinical feature of BV is the increased vaginal discharge with fishy odor. The diagnostic specificity of Nugent scoring system is high. Gardnerella vaginalis is the predominate bacteria in BV with deficiency of lactobacillus. There is significant high prevalence of U.urealyticum, M.hominis and C.trachomatis in women with BV. The recurrent BV is existed. |
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