Research On Pure Titanium Microneedle Plastic Forming And Numerical Simulation

Miniaturization of product has become a unstoppable trend inmanufacturing industry, especially in Communication Electronics, Micro-System Technology, MEMS(Micro Electro Mechanical System), etc. Inmedical field, micro-needle for transdermal drug delivery is widely used.Plastic micro-forming, which has inherited traditional advantages of plasticprocessing technology, such as high production efficiency, high materialutilization rate, sound mechanical properties of products, was applied torealize manufacturing of micro-needle in this paper. The main achievementsobtained are as follows:(1) Pure titanium TA1was chosen as the forming material ofmicro-needle. Tensile tests of TA1plates were done, on basis of whichdifferent thicknesses of material and different tensile speeds were analyzed toexplore the influence of these two factors may have on forming performanceof TA1plates. Experimental phenomena were explained through the micro-forming theory and plastic forming mechanism of pure titanium. The optimalTA1micro-needle forming condition was achieved by contrast.(2) According to the shape and size of the researched titanium micro-needle, upsetting-extrusion technology was selected to form it. Two differentupsetting-extrusion dies for micro-needle was designed, and suitableprocessing method and effective testing equipment were applied to guaranteeconformity of die to the test requirements. Experiments of micro-needleforming with different strain rates, different thicknesses were conducted. (3) By utilization of SEM (scanning electron microscopy), morphologyof micro-needle was observed, and the force-displacement curve of resultswas analyzed. Analyze micro-needle upsetting extrusion forming press-displacement curve to obtain how thickness, forming speeds and differentmould shapes influence on the force-displacement curve.(4) With help of DEFORM-3D FEA software, material model related tostrain rate of the pure titanium TA1was defined, and upsetting-extrusionforming of micro-needle was analyzed. By comparison, the simulation resultwas found to be consistent with the experimental result.(5) Choose extrusion technology for micro needle array forming, useDEFORM-3D software to analysis micro needle spacing and micro needleposition influence on micro needle array forming effect, guide micro needlearray extrusion die design.