Synthesis And Characterization Of Phosphine Heteroaryl Pyrazole And The Metal Complexes Of Imidazole Derivatives And Research On Catalysis

This paper is divided into two parts：Firstly, because the phosphine heteroaryl pyrazole can form stablemetal organic complex compouds with metal ions, it plays a veryimportant role in medicine and biochemistry, and superconductingmagnetic material field.This article mainly based on3,5–dihydro-1,2,4-diazaphosphole,2,6-bis(1-methyl-3,5-dihydro-diazaphosphole)pyri-dine ligand and metal nickel, cobalt, zinc, cadmium, copper and othermetal salts,synthesized metal organic complexes, and that wasdetermined byusing NMR,infrared analysis insttiment,XRD diffractioninstrument and so on.Secondly, this article synthesized nine novel heterocycliccarbenes bridged by big substituent, these new compounds containN-heterocyclic carbenes precursor So it can be used as the phasetransfer catalysts applied to a series of chemical reactions,estimatedthe catalytic abilities in the Suzuki coupling reaction. As follows: (1) A series of novel N-heterocyclic carbene ligands weresynthesized by the substitution reaction with imidazole as rawmaterial and that was determined byusing NMR,infrared analysisinsttiment,XRD diffraction instrument and so on.(2) NHC metal complexes were obtained by some transition metalliccompounds and also characterized by NMR.(3) The new compounds were evaluated to catalyze Suzuki couplingreaction in different solvents, bases, catalysts, reaction substratesand reaction conditions. Experimental results shown that KOH andDMF: H2O=1:1were the optimal bases and solvents, these compoundsexhibited good activity in Suzuki reaction with phenyboronic acid andbromobenzene.The work of this paper provides the relevant data for the furtherinvestigation on biology, medicine, materials, catalysis field.