| The total morbidity of pregnancy induced hypertension (PIH) was 9. 4%. The complications of PIH include fetal embarrassment, intrauterine growth retardation and perinatal death. Many literatures reported about uterine artery, fetal umbilical artery, renal artery and middle cerebral artery in pregnant women with PIH. But the detection of placenta! bed arteriole was rarely reported. In our study, we detected changes of umbilical artery, mainly of placenta! bed artery. Pla-cental bed vessels were reconstructed by three - dimensional method at the same time. We observed three - dimensional color power angiogra-phy (3D -CPA) of placenta in normal pregnant and PIH women.Materials and methodsPatients PIH group and normal matched group. In PIH group, 49 cases diagnosed as PIH in our hospital from October, 2000 to February , 2002 were examined by color Doppler ultrasound after the 30th week of gestation, of which 15 cases were mild PIH, 21 cases were moderate PIH, and 13 cases were severe PIH. All the patients had not been treated before the examination. The classification of PIH was according to Gynecotokology (edited by Le jie, 5l edition).The matched group was normal pregnant women without pregnant complications matching in gestational age, such as diabetes , kidney disease.Contents Color Doppler ultrasound was used to detect placental bed artery and umbilical artery, the indices included pulsatility index ( PI) , resistance index ( RI) , systolic maximum velocity ( Vmax) /di-astolic minimum velocity ( Vmin) ( S/D) , time average velocity(TAV) . At the same time, the placenta! bed blood vessels of normal pregnant and PIH women was studied in three - dimensional method in order to observe the changes of spacial structure.Methods We used Medison 730 D four - dimensional color Doppler ultrasound equipment with 3 - 5 MHz scanner. The gravidas took supine posture. We measured the blood flow parameters of pla-cental bed artery and umbilical artery . The measurement of umbilical artery was 2 ~3cm to the site that umbilical cord entered the placenta , where the pressure gradient was small and relatively fixed. The measurement of placental bed artery ; Umbilical artery separated several branches and entered the placenta , we Chose one of these arteri-oles and set the sampling line parallel to the vessels. The angle between the ultrasound beam and blood flow should be controlled within 15 . We froze the screen when acquiring satisfactory spectrum and took the mean value more than three cardiac cycles.Statistics treatment All of values were expressed as mean value ?standard error. We used t - test to compare the parameters between groups. P <0. 05 was considered to be significant, P <0.01 was considered to be marked significant. All the parameters were analyzed by SPSS 10. 0 statistic software.ResultsWe measured the blood flow parameters of placental bed artery in normal gravidas at different gestational age. The results prompted that; with the increase of gestational age, the placental function became maturer. The results were that the resistance indices ( PI, RI, S/D) of placental bed arteriole decreased, while TAV increased. The difference between 34-38 gestational weeks group and 30 - 34 gestational weeks group wasnt significant, which illustrated that after 30 -34 gestational weeks, all the parameters of placenta! bed arterioles tended to be stable.We measured the blood flow parameters of umbilical artery in normal gravidas at different gestational age. The results prompted that; with the increase of gestational age, the placental function became maturer. PI, RI, S/D of umbilical artery decreased gradually, while TAV increased gradually. After 30 -34 gestational weeks, all the parameters tended to be stable.We measured the blood flow parameters of placental bed artery in PIH patients. The results prompted that; compared with the normal gravidas, the resistance indices (PI, RI, S/D) of placental bed artery in PIH patients were higher, while TAV was lower. Compared with the mild... |
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