Paul God Tang Treatment Of Depressive Neurosis And Depressive Neurosis With Il-1¦Â, Il-2 Relations

To understand the relationship between the depressive neuroses and interleukin-1β (IL-1β ),interleukin-2(IL-2),and to investigate whether IL-1 β , IL-2 can be regarded as diagnosis index to depressive neuroses. In this study, emzyme-linked immunosorbent assay(ABC-ELISA) were used to detect the content of IL-1β and IL-2 in the blood, serum of 30 depressive neuroses patients and 10 healthy person. At the same time, the depressive neuroses group was treated with Baoshen Decoction for six weeks, HAMD were used to measure their scores before and after the treatment to observe and evaluate its curative effect. The result showed that the content of IL-1 β in depressive neuroses group is significantly higher than the control group (P<0.05),but there is no significant difference between the two group as for IL-2,(P>0.05).Positive correlations exist between IL-1β, IL-2 and course respectively. And the total effective rate is about 93.33%.In conclusion,IL-1β is more sensitive than IL-2 and both of them have positive correlation to course.IL-1β can be used as a reference standard for diagnosis of depressive neuroses. Baoshen Decoction has obvious anti-depression effect.