| To observe the clinical effect and blight of YiQi TongMai(YQTM) oral Liquid to patients with stable angina, which belong to Qi deficiency and Blood stasis by TCM Bianzheng. To evluate objectively the validity and security of YQTM oral liquid in treating.Methods:The qualified test-acceptors were randmoly divided into treated group and control group in propotion to 1:1. They were given the drugs on time order. The remedial drug and simulant drug were numbered at random and double-blind. YQTM oral liquid and ShuXin(SX) oral liquid were used to remedial drug and contrust drug. The administration of YQTM oral liquid was one piece a time,three times a day,the other one was one piece a time,two times a day,both four weeks. Placebo was used in the difference.According to the observed results,evaluated thetreatment effectiveness:1 .The indicatrixes of treatment effectiveness. (1) Accumulated score of sympotum and sign;(2)Electrocardiograph (ECG) changing ofST-T.(3) Blood lipid and Hemorrheologic tests.(4)The changes of nitroglycerin comsumption.2.Security tests include the three frequent exams.liver and kidneyfunction.At last,analysed the statistic data with one side test.When p < 0.05,it wasconsidered as statistic meanings.Result:After four weeks treatment,both groups can improve significantly the clinic sympotums(P <0.01)reduce blood lipid(TGTC) ( P < 0.05)lighten the degree of ischemic changes in ECG and hemorrheologic(P< 0.05).There is no significant difference between the two groups hi reducing blood lipid and improving the degree of ischemic changes inECG ( P > 005 ) The total treatment effect is similar ( P > 005 ) But the treated group is significantly better than the control one in improving symptom and hemorrheologic andreducing blood lipid(P < 005 ) .Conclusion:By four weeks treatment,the clinic effect of YQTM is a little superior to SX,but in improving symptom and hemorrheologic,and reducing blood lipid, YQTM is much better than SX.Therefore, YQTM is adapt to patients with stable angina,which belong to Qi deficiency and Blood stasis by TCM Bianzheng. It was considered as statistic meanings.lt has been certified a safe and effective prescription of Chinese herbal meadicine by clinic experiment. |