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The Volts Nine Sticking Therapy Research On The Impact Of Sensitized Guinea Pig Bronchoalveolar Lavage Fluid Mc And Lung Tissue Morphology

Posted on:2006-02-13Degree:MasterType:Thesis
Country:ChinaCandidate:X Y JinFull Text:PDF
GTID:2204360152999275Subject:Chinese Academy of Pediatrics
Abstract/Summary:PDF Full Text Request
Bronchial asthma (BA) is a common respiratory tract affection that greatly harms children's health. The course of asthma is long, and the recurrent attack is very often. Asthma belongs to stubborn disease. There is much experience about asthma in Traditional Chinese medicine (TCM). It is considered in TCM that asthma owes to functional disorder of lung, spleen and kidney. Functional disorder of organ results in endogeny insidous phlegm which is induced by exogenous evil, then asthma break out.To find out the relationship between TCM pathogenesis and modern pathomechanism. The article analyzes different points in pathomechanism of TCM and modern medicine. It is considered in TCM that sputum is insidious in lung and the whole body, while it is considered in modern medicine that chronic inflammation is in air passage.Brief introduction of point application therapy at certain solar term and the mechanism of action. Point application therapy at certain solar term is a particular external treatment of TCM in traditional medical science, and has been used to cure asthma for many centuries. Point application therapy at certain solar term is based on TCM meridian theory that has many kinds of therapeutical effects. Herb irritates part meridian point and provokes meridian-QI all over the body. Besides herbs with high concentration accumulates in lung, and the best pharmacological action also is achieved through blood circulation.To study the effect of mast leukocyte's appearance and lung histomorphology that point application therapy at certain solar term cure allergized cavies. Method: 40 healthy juvenil cavies were given intraperitonealinjection with 10% egg protein solution according to 0. 4ml/100g, and allergized with 1% egg protein solution atomization after two weeks. Allergized cavies were divided into three groups that were control, corn control and treatment roup. Treatment group was given point application therapy on Feishu, Dazhui, Dingchuan, Tiantu and Shanzhong with herbs. Corn control was given point application therapy with corn meal. Healthy cavies were selected as normal group, control and normal group weren't given any treatment. Result: There are many inflammatory cells in allergized cavies' BALF and many MC and EOS infiltrated lung histomorphology which consistents with asthma pathological transform. BALF's MC decreased in Treatment group and lower than control group (P < 0. 05) .Conclusion: point application therapy can relieves asthma through lessening inflammatory reaction of air passage, which may be the main mechanism.
Keywords/Search Tags:bronchial asthma, animal model, mast cell, histomorphology
PDF Full Text Request
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