Propofol Target-controlled Infusion With Artificial Infusion Used For The Comparison Of Abortion

Objective: To compare anesthesia qualities , hemodynamic, respiration and adverse reactions of target-controlled infusion (TCI) of propofol with that of manually controlled infusion(MCI)of propofol on induced abortion. Methods: 100 pregnant women undergoing induced abortion were randomly divided into two groups: group M was manually controlled infusion of propofol. It was administrated propofol 2mg/Kg by intravenous injection after disinfection, and administering 0.5—1.0mg/Kg boluses according to the patient's needs; group T was target-controlled infusion of propofol, the target plasma concentration was set for induction on 5ug/ml,then titrated according to the patient's needs throughout the procedure. Analgesic qualities, cervical dilatation degree, time to loss consciousness, recovery time, discharge time and the dosages of propofol were recorded as well as MAP, HR, SPO₂ of 1 min before administering (t1),1 min after dilatation of cervix(t2),1 min after induced abortion (t3),after operation(t4) and the patients awakening(t5);Case with moving , the back of the tongue in operation and dazzle after operation. Results: there were no significant differences in time to loss consciousness, recovery time, discharge time between two groups (P>0.05).Mean dose of propofol was higher in group T than that in group M(p<0.05);The anesthetic efficacy in group T was better than that in group M; MAP in group M was significant decrease than that in group T(p<0.05)there was no significant differences in change of HR between the two groups (p>0.05).there were more cases with respiration depressed, moving, the back of the tongue in the operation and the incidence of dazzle after operation in group M than that in group T(P<0.05). conclusion:The better anesthetic efficacy and the fewer adverse reactions of TCI compared with MCI of propofol on induced abortion.