Study Of The Quality Standards Of The Shu Chest

This paper is about quality standard of Shuxiong tablet,which is composed of Radix Notogingseng, Flos Carthami, Rhizoma Chuanxiong. In Chp2000, Radix Notogingseng and Rhizoma Chuanxiong in Shuxiong tablet were identified by TLC, ginsenoside Rg₁ in Shuxiong tablet was determined by TLCS. In this paper ,Radix Notogingseng, Flos Carthami and Rhizoma Chuanxiong in Shuxiong tablet were identified and notoginsenoside R₁, ginsenoside Rg₁,hydroxysafflor yellow A and ferulic acid in Shuxiong tablet were determined. Above methods provided a qualitative and quantitative basis for the quality standard of Shuxiong tablet.Radix Notogingseng, Flos Carthami and Rhizoma Chuanxiong in Shuxiong tablet were identified by TLC with the posts clear and reproducible.The Hydroxysafflor yellow A was separated from the extraction of safflower by column chromatography on polyamide, followed by preparative liquid chromatography. The structure was elucidated by UV,IR,MS,¹H-NMR and ¹³C-NMR,The content of hydroxysafflor yellow A was 98.1%.Hydroxysafflor yellow A in Shuxiong tablet was determined by HPLC. It had good linearity within the rang of 1.02-10.2 μ g · mL^-1, The average recoveries was 98.2%(RSD=1.2%).Simultaneous determination of notoginsenoside R₁ and ginsenoside Rg₁ contents in Shuxiong tablets by HPLC . They had good linearity within the rang of 2.5-49.6 μ g ·mL^-1(r=0.999 7), 23.6-472.0 μ g ·mL^-1(r=0.999 9), respectively. The average recoveries of them were 98.9% (RSD=2.5%), 99.1% (RSD=2.2%), respectively.Ferulic acid in Shuxiong tablet was determined by HPLC. It had good linearity within the rang of 1.94-19.4 μ g · mL^-1(r=0.999 8). The average recoveries of it was 98.4%(RSD=1.6%).