Detoxifying Cream Soup Experimental Study Of The Treatment Of Systemic Lupus Erythematosus

Background and Objective: SLE is a kind of autoimmune disease that affects many systems of the body. It is found more often in young females. Clinically it has a variety of symptoms which occur repeatedly and tissues and organs like joints, muscles, skin and the kidneys are mostly involved. The cause of SLE is unknown, but generally it is believed to be related to heredity, virus infection, intake of some medicines, exposure to ultraviolet ray and disturbance of endocrine function. However, due to its uncertain pathogeny, there is no specific and pertinent drug.SLE is considered to be of the category of "bi zheng" (arthralgia-syndrome) ,"yin yang du"(lupus erythematosus discoides),"gui lian chuang"(facial erythema).Insufficiency of congenital disposition, lack of nourishment after birth, or seven emotional upsets complicated by exposure to sunlight and attack of six exogenous factors are the causes of the disease ; imbalance of yin and yang , stagnation of qi and blood and blockage of meridians are its pathogenesis. Mainly on the basic of syndrome differentiation and treatment and through multi-layer, multi-loop, multi-method and multi-target way , it has great advantage to anti-inflammatory, analgesia, regulating immune function and prevent the development of disease. The research topic lies on the experience of national famous Professor Wang Lvqiu and mentor Professor Wang Yue. We develop the "Jiedu Quban Tang", which is on the basic of their theory and experimental prescription. We study the effects of "Jiedu Quban Tang "on SLE, and discuss the mechanism so as to provide experimental and theoretical basis for SLE's therapeutics.Methods: There are three parts as follows: (1) The pain caused by the hot-board and acetic acid-induced writhing in mice were established as the experimental models to test the analgesic effect. (2) Xylene-induced ear...