Systematic Reviews Of Acupuncture-related Treatment Of Primary Dysmenorrhea

According to the literature in recent years, the mechanism of primary dysmenorrheal includes two different parts: The Chinese Medicine thinks it is caused by bruise of"Qi"and"Xue", which dues to"Shi"or"Xu"in the human body, and there are different treatments for different types of dysmenorrheal; The Mordern Medicine considers that primary dysmenorrheal is closely related to plasma prostaglandin (PG) level which can cause uterine contraction and spasm pain, and dysmenorrhea is commonly treated with nonsteroidal anti-inflammatory drugs (NSAIDs), prostaglandin antagonist, and antispasmodic and analgesic drugs.They work fast, but they have some side effects. As non-pharmacological interventions, acupuncture related therapies may be valuable and potential, however, there were not enough evidence to prove this, therefore, and the further study is needed urgently.Systematic review of clinical trials of acupuncture related therapies for primary dysmenorrheaObjective The aim of this study was to assess the clinical effectiveness of acupuncture related therapies for primary dysmenorrhea.Search Strategy A specified literature search was performed on Cochrane Library, MEDLINE, EMBASE, CNKI database, CBM database and VIP database. Selection Criteria All relevant clinical controlled trials about acupuncture related therapies for primary dysmenorrhea were included, and the qualities of trials were assessed.Data Collection and Analysis Two independent reviewers were responsible for data extraction and assessment. The original data of each trial were analyzed with software Revman 4.2, but the meta-analysis couldn't be carried out because of the heterogeneity of the trials.Main Results Thirty randomized controlled trails (RCTs) and 2 controlled clinical trials (CCTs) were identifed with 3910 patients where 2278 patients received active treatment. Most trials were of low methodological quality (6 trials were Grade B, and 26 trials were Grade C). Data analysis indicated that there were conflicting results regarding whether acupuncture related therapies were more effective than controls. However, there was a small trial but methodologically sound trial of acupuncture which suggested acupuncture was significantly more effective than control groups (Placebo acupuncture: WMD was -0.57, 95%CI [–0.76,–0.38], P<0.00001; standard control: WMD was -0.19, 95%CI[–0.37,–0.01], P=0,04; visitation control: WMD was -1.04, 95%CI [–1.28,–0.80], P< 0.00001).Conclusions Because of low methodological quality and small sample, there was no fully convincing evidence for acupuncture treatment on primary dysmenorrhea. There is an urgent need for randomized, blinded, placebo controlled trials to assess the effectiveness of acupuncture treatment. Clinical Obseration of Electroacupuncture in SP6 Primary DysmenorrheaObjective: To find the study method and observe the difference of effect between SP6 and no-acupoints for primary dysmenorrheal Method: Fifteen patients were divided into 5 groups according to the random figure table, three patients in each group. The 5 groups were as follows: SP6; no-acupoint beside ST33; no-acupoint beside GB39; no-acupoint beside SJ6; no-acupoint beside LI13.All treatments begun when the pain occurred, once a day and lasted for three days. The outcome index were Visual Analogue Scale (VAS) and Retrospective Symptom Scale (RSS).They were observed before treatment and 5 min, 10min,30min, 60min after treatment. Result: From the result of RSS, there were no difference among the five groups.From the result of VAS, the effect of SP6 group seemed to be better than the other four groups in 5min, 10min and 30min after treatment; the effect of no-acupoint beside LI13 group seemed to be better the others in 60min after treatment ;the effect of no-acupoint beside GB39 was the worst appulsively than the other four groups in 5min , 10min after treatment, and ;the effect of no-acupoint beside SJ6 seemed to be the worst than the other four groups in 30min , 60min after treatment. Discussion: As the sample in the trial was too small, the difference was not obvious among the five groups. There is an urgent need for large sample trial to assess the effectiveness of acupuncture treatment.