The Age In Anomic Aphasia Morning And Evening Of Spontaneous Rehabilitation Effect

[Aims]An increasing number of studies are being conducted on the effect of age of acquisition(AOA) on word processing, usually at a certain point of time. My researches are tocomprehend the real mechanism and traces of AOA in the brain, as well as real AOAeffects in the early and late spontaneous recovery from anomia.[Subjects & Methods]Experiment 1: basic language examinations, visual perception test.Experiment 2: We designed an overt picture naming task and tested a Chinese anomicsubject at 10 days, 22 days, and 12 months post-onset; we then constructed recoverygraphs and performed a logistic regression analysis by SPSS.Experiment 3: We designed an fmri study including picture naming tasks at 22 dayspost-onset, and then used SPM2 to analyze the data.[Results]This case was a classical anomia. AOA was not significant in the total recovery althoughit played an important role in the early recovery, while familiarity was always significant.Right BA 37 is more active when the patient retrieved the word and was able to name.[Conclusion]We suggest that the result may be related to the obviously dissimilar pathologicalprocesses and fmri data provides new evidences and supports the hypothesis of Ellis. Wehypothesis that pictures' information is collected by bilateral BA 18 and then sent toangular gyrus through left BA 37/19. Right BA 18 usually sent the information to rightBA 37/19 and then sent to left BA 37/19 through corpus callosum. Low AOA word canbe sent directly to angular gyrus to angular gyrus, however, it is depressed in the healthsubjects.