Glucose And Liver Fried Treat Type 2 Diabetes (t2dm) And Fatty Liver Clinical Research

Objective:To observe the traditional chinese medicine TGJ in type 2 diabetes(T2D-M)and fatty liver in patients withBMI,FBG,P2hBG,FINS,P2hINS,HOMA-IR and TG,TC,H DL,LDL,ALT,AST,Iiver type-B ultrasonicand the Chinese medicine clinic-alsymptoms impact.To analyse the mechanism of TGJ and explore the side of the clinical value.Method:1 Those cases were diagnosed as type 2 diabetes and fatty liver,spleen deficiency TCM Liver depression for 80 patients,accroding to the order of treatment were randomly divided into treatment and control groups by each 40 cases.The control group used Repaglinide-Chennai(NovoNorm),daily 1～3mg;or acarbose(BaitangPing),daily50～1-50mg;subcutaneous injection of insulin or hypoglycemic,and other conve-ntional,and also used the prototype Glutathione protective treatment,daily 1200mg,in-travenous drip,with consecutive seven days,and then change to oral glutat-hionechip,400mg,tid. On the basis of the control group the treatment group therapy adds traditional Chinese medicine with TGJ(Bipleurum,white tricks,TGP,Angelica,Yinchen,Fulin,etc.)to treat, daily,decocted from the hospital room to 400ml,at 2 bags,in the morning and evening taking a bag.Match for a course of treatment,even serving two courses.2 To observe the two groups of patients with clinical symptoms and signs(such as: gastric cavity or flank pain,abdominal distention,less drinkingand eating,having loose bowels.Emotional depression or impatient irritability,like to suspire,break wind,abdominal pain and reduced pain after the crash.Red tongue and white or greasy moss,pulse string or thin,etc.),and fill out the type 2 diabetes and fatty liver depression and spleen deficiency symptom of Traditional Chinese Medicine point to quantify table.3 To observe BMI,FBG,P2hBG,HbA1c,FINS,P-2hINS,HOMA-IR and TG,TC, HDL,LDL,ALT,AST,liver type-B ultrasonic,before treatment and after treatment of the ins-pections.4 security laboratory observation4.1 Blood-RT,Urine-RT,Liver and kidney function;ECG examination.Coagulation function.Routine examinations once a week,four weeks after 2～4 weeks for a check-up. Liver and kidney function every 4 weeks for a check-up.Coagulation 2～4 weeks for a check-up.4.2 Adverse Reactions:To observe patients taking the drug after any discomfort,and the combination of blood,liver and kidney function and blood coagulation inspection of the observation of a non-toxic drug side effects.5 Statistical Methods SPSS12.0 statistical analysis software calculation.All measure ment data with(?)±S(mean±standard deviation),t test;Count information is X~2 test; grading information is Ridit analysis.Result:1 Control group and treatment group clinical symptoms and signs compared changes: treatment group total effective rates were 92.50%;while control group was 65.0%; the total therapeutic effect of treatment group was better than that of control group(P＜0.05).2 Treatment group could improve the patients,clinical symptoms and signs,the effects was better than control group(P＜0.05 or 0.01).3 In the sides of BMI,FBG,P2hBG,HbA1c,FINS,P2hINS,HOMA-IR andTG,TC, HDL,LDL,ALT,AST,Iiver type-B ultrasonicand so on,treatment groupwas better than con-trolgroup(P＜0.05 or 0.01).Chinese medicine TGJ can significantly alleviate type 2 diabetes and fatty liver in patients with various clinical symptoms and signs, can effe-ctively improve insulin resistance,regulation of glucose and lipid metabolism and re-duce the liver enzyme.It bears the role of regulation of multi-system,multi-target,the overall characteristics.