Evaluation Of Coronary Artery Disease Patients With Drug-eluting Stent Placement Before And After The Quality Of Life

In recent years, the incidence of coronary heart disease (CHD) has increased obviously as the improvement of living standard. With the world economy and technology development, the coronary heart disease treatment had been developed from simple drug therapy to coronary artery bypass and interventional therapy. The use of drug-eluting stent make in-stent restenosis incidence further reduce in the treatment of percutaneous coronary intervention. More patients with coronary heart disease is the survival status of disease. Because of the change of medical model, people come to realize the disease treatment of traditional clinical results-survival, life extension and symptom relief has gone. To select the treatment methods in patients with coronary heart disease, we not only pay attention to its various physiological improvements, we but also should focus on the overall health of the patients. So the scholars have proposed the concept of quality of life. In recent years, many research have showed that coronary stenting can significantly improve the quality of life of CHD patients. Other studies have proved that the amount for coronary heart disease, in the table of the SAQ has good repeat reliability, content validity, construct validity and response, and the response rate is better than other scale. Since the use of drug-eluting stent, there is less study of coronary drug-eluting stent grafts life quality evaluation, and is lack of overall research. This text researched the quality of life patient used drug-eluting stent with SAQ.Objective:To evaluating the quality of life in CHD patients before and after coronary intervention therapy, looking for the factors that affect or improve the quality of life and then seeking a more appropriate treatment in future clinical work.Methods:210 patients who received PCI in department of Cardiology Jincheng coal Group General Hospital from March 2008 to September 2009 were enrolled consecutively. All patiets received drug-eluting stents and meet the inclusion criteria. The question nary were filled before the operation and date of demography and clinical medicine, including:age, gender, occupation, education level, the average monthly income, marital status, medical diagnosis, hypertension, diabetes, blood lipid and smoking history were collected. General pharmacological treatments were given, including:aspirin and clopidogrel, P-receptor antagonists, lipid nitrate drugs, Statins; And if the patients combined with Hypertension and/or Diabetes Mellitus, drugs for controlling blood pressure and/or blood glucose were added.198 cases finished the follow up; the follow-up visit rate is 94.29%. The Seattle angina pectoris scale scores cordial function, and serum lipid levels were recorded before and after 6 months of PCI.Result:Coronary angiography showed that one-vessel stenosis in 48 cases, two-vessels stenosis in 86 cases and three-vessels stenosis in 64 cases. In these cases,92 cases were implanted one stent,50 cases were implanted two stents,56 cases were implanted three or more stents. The scores about physical limitation, treatment satisfaction, angina frequency scale, angina stability scale, disease perception scale were all higher than that in the preoperative (P =0.000); Compared to the preoperative, the score of Disease perception scale, treatment satisfaction had significant differences in the patients with different cultural level (P=0.000). However, there were no significant differences in the disease awareness,treatment satisfaction in the patients with different cultural level (P>0.05). The scores about physical limitation and treatment satisfaction were improved in patients with Angina pectoris, Acute myocardial infarction, old myocardial infarction post operation (P=0.000). Compared with preoperative, the EF was significant improved in patients with angina pectoris and AMI but not OMI. All of the patients, the total cholesterol, low-density cholesterol were decreased and the high-density cholesterol was increased after 6 months (P=0.000).Conclusion:The quality of life in patients with CHD and the cardiac function in patients with angina pectoris or acute myocardial infarction were significantly improved after Drug-eluting stents implantation; Meanwhile, use of Statins can reduce the total cholesterol low density cholesterol and increase the high-density cholesterol.